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Flashcards in Alcohol Dependence Deck (7)
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1
Q

What drugs are used for alcohol withdrawal?

A
  • Diazepam / Chlorodiazepam
  • Oxazepam (if liver damage present)
  • Chlordiazepoxide
2
Q

What supportive treatment is provided for alcohol abuse patients? Why?

A
  • Oral Thiamine
  • IM/IV Pabrinex (C, B1, B2, B3, B6)

-B vitamin body stores are scarce

3
Q

Why is it essential to provide Thiamine to alcohol abuse patients?

A

Their B vitamines are likely to be depleted.
Thiamine is a coenzyme involved in the Krebs cycle.
Metabolism in the absence of Thiamine is anaerobic, producing lactic acid. Brain damage can follow.

4
Q

What is Wernicke-Korsakoff syndrome? What’s the treatment?

A

Thiamine deficiency syndrome

Pabrinex

5
Q

What pharmacological treatment is used in relapse prevention?

A

Disulfiram - aggravates immediate hangover

Acamprosate - neuroprotective

6
Q

What is delirium tremens?

A

Rapid onset of confusion following withdrawal of alcohol

7
Q

What is Alcoholic Hallucinosis?

A

Acoustic hallucinations, delusions and mood disturbances occuring during or shortly after major bouts of drinking.
-tend to be reversible