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Cc2mtap > ALKALINE PHOSPHATASE > Flashcards

ALKALINE PHOSPHATASE Flashcards

1
Q

Alkaline Phosphatase ALSO KNOWN AS

A. Alkaline Orthphosphoric Phosphohydrolase
b. Alkaline Orthophosphoric Monoester Phosphohydrolase
c. Alkaline Orthophosphoric Monoester Phosphohydroxide

A

b. Alkaline Orthophosphoric Monoester Phosphohydrolase

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2
Q

A hydrolase which catalyzes the hydrolysis of the phosphomonoester bonds at an alkaline pH

A

ALKALINE PHOSPHATASE

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3
Q

Optimum pH of alkaline phosphatase

a. 10-15
b. 9-10

A

b. 9-10

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4
Q

Liberates inorganic phosphate from an organic phosphate ester with
production of alcohol

a. acid phosphatase
b. alkaline phosphatase

A

b. alkaline phosphatase

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5
Q

activator of alkaline phosphatase
a. NaCl
b. Mg2+

A

Mg2+

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6
Q

reaction Alkaline Phosphatase
a. ALCOHOL + PHOSPHATE ION+NAD
B. ALCOHOL + PHOSPHATE ION+NADH
C. ALCOHOL + PHOSPHATE ION

A

C.ALCOHOL + PHOSPHATE ION

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7
Q

The 4 major sources of ALP

A
  1. Liver
  2. Intestine
    3.Placenta (among pregnant women)
  3. Bone (osteoblast)
    renal tissues/ kidney

“LIP BR”

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8
Q

Among healthy individuals, the predominant alkaline phosphatase present in healthy sera is derived from the _______ & _____.

a. liver and bones
b. skeletal and renal

A

a. liver and bones

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9
Q

AP is used for the evaluation of hepatobiliary disorders such as ____

a. Osteitis deformans
b. Obstructive disease of liver and biliary duct

A

. Obstructive disease of liver and biliary duct

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10
Q

T OR FALSE
alkaline phosphatase is liver specific

A

FALSE NOT LIVER SPECIFIC

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11
Q

example of cofactor that enhances the enzyme activity by altering the spatial configuration of the active site of enzyme/ enzyme-substrate binding
process

a. coenzyme
substrate
c. activator

A

c. activator

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12
Q

Elevated ALP IS CORRELATED WITH

A. bone disorders and cardiac disorders
b. hepatobiliary and bone disorders

A

b. hepatobiliary and bone disorders

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13
Q

assay used in alkaline phosphatase

a. Regan ALP
b. Nagao ALP
c. szasza
d. Bowers and McComb

A

d. Bowers and McComb

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14
Q

Based on molar absorptivity of p-nitrophenol

a. Cherry Crandall
b. Tietz
c. Roy and Hillman
d. Bowers and McComb

A

d. Bowers and McComb

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15
Q

the color reaction of ALKALINE PHOSPHATASE UNDER BOWERS AND McComb

a. red
b blue
c. yellow

A

c. yellow

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16
Q

REACTION OF BOWERS AND MCCOMB

A. ALCOHOL + p- Nitrophenol +Phosphate ION
B. A.ALCOHOL + p- Nitrophenol +Phosphate ION+NAD

A

A. ALCOHOL + p- Nitrophenol +Phosphate ION

Cc2mtap (20 decks)

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