LDH ISOENZYMES Flashcards

1
Q

LDH-1(HHHH)
TISSUE

A. Heart, RBC
B.Liver
C.Lung, spleen, pancreas
d. Skeletal Muscle

A

A. Heart, RBC

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2
Q

Disorders (↑) in LDH-1(HHHH)

a. Renal Infarction, Megaloblastic anemia
b. Myocardial Infarction, Hemolytic anemia
c. Hepatic injury
d. Skeletal muscle injury

A

b. Myocardial Infarction, Hemolytic anemia

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3
Q

LDH-2 (HHHM)
TISSUE

A. Heart, RBC
B.Liver
C.Lung, spleen, pancreas
d. Skeletal Muscle

A

A. Heart, RBC

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4
Q

LDH-3(HHMM)
TISSUE

A. Heart, RBC
B.Liver
C.Lung, spleen, pancreas
d. Skeletal Muscle

A

C.Lung, spleen, pancreas

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5
Q

LDH-4(HMMM)

A. Heart, RBC
B.Liver
C.Lung, spleen, pancreas
d. Skeletal Muscle

A

B.Liver

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6
Q

LDH-5(MMMM)

A. Heart, RBC
B.Liver
C.Lung, spleen, pancreas
d. Skeletal Muscle

A

d. Skeletal Muscle

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7
Q

Disorders (↑) in LDH- 2(HHHM)

a. Renal Infarction, Megaloblastic anemia
b. Myocardial Infarction, Hemolytic anemia
c. Hepatic injury
d. Skeletal muscle injury

A

a. Renal Infarction, Megaloblastic anemia

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8
Q

Disorders (↑) in LDH- 3(HHMM)

a. Renal Infarction, Megaloblastic anemia
b. Myocardial Infarction, Hemolytic anemia
c. PULMONARY EMBOLISM
d. Skeletal muscle injury

A

c. PULMONARY EMBOLISM

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9
Q

Disorders (↑) in LDH- 4(HMMM)

a. Renal Infarction, Megaloblastic anemia
b. Myocardial Infarction, Hemolytic anemia
c. PULMONARY EMBOLISM
d. HEPATIC INJURY

A

d. HEPATIC INJURY

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10
Q

Disorders (↑) in LDH- 5(MMMM)

a. Skeletal muscle Injury
b. Myocardial Infarction, Hemolytic anemia
c. PULMONARY EMBOLISM
d. HEPATIC INJURY

A

a. Skeletal muscle Injury

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11
Q

Normal Values range of LDH- 5(MMMM)

A. 20-30%
B.20-25%
C. 30-40%
D. 7-15%
E. 5-15%

A

E. 5-15%

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12
Q

Normal Values range of LDH-1(HHHH)

A. 20-30%
B.20-25%
C. 30-40%
D. 7-15%
E. 5-15%

A

A. 20-30%

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13
Q

Normal Values range of LDH-2(HHHM)

A. 20-30%
B.20-25%
C. 30-40%
D. 7-15%
E. 5-15%

A

C. 30-40%

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14
Q

Normal Values range of LDH-3(HHMM)

A. 20-30%
B.20-25%
C. 30-40%
D. 7-15%
E. 5-15%

A

B.20-25%

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15
Q

Normal Values range of LDH-4(HMMM)

A. 20-30%
B.20-25%
C. 30-40%
D. 7-15%
E. 5-15%

A

D. 7-15%

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16
Q

Not normally seen among healthy induvial; only demonstrated when the
patient has the ff conditions:

Drug hepatotoxicity, Obstructive jaundice and arteriosclerotic failure

A

LDH6 (Alcohol Dehydrogenase)

17
Q

fastest to migrate//closest to anode;

A

H-Heart; M-muscle; LDH 1

18
Q

slowest/farthest

A

LDH 5

19
Q

Concentration in Healthy Human Serum:

A. LDH 2 > 1 > 3 > 4 > 5
B. LDH 1 > 2 > 3 > 4 > 5

A

A. LDH 2 > 1 > 3 > 4 > 5

20
Q

Acute MI and Intravascular Hemolysis

A. LDH 2 > 1 > 3 > 4 > 5
B. LDH 1 > 2 > 3 > 4 > 5

A

B. LDH 1 > 2 > 3 > 4 > 5

21
Q

↑ LDH-1 & ↑ CK-MB

a. Intravascular Hemolytic Condition
b. AMI

A

b. AMI

22
Q

↑ LDH-1 & Normal CK-MB

A

INTRAVASCULAR HEMOLYTIC