Flashcards in Allergy and Immunology Deck (10):
How do you screen for a terminal complement deficiency?
Get a CH50 level
What complements are used to follow disease activity in SLE?
C3, C4, and CH50
Which complement is a good screen for complement deficiencies?
Consider what complement deficiency in patients with early-onset SLE?
To determine if you should step up therapy for asthma treatment, follow the rule of 2's. What is that rule?
Step up therapy for any of the following:
- asthma symptoms during the day >2x/week
- night time awakenings >2x/month
- ED visits/admissions for asthma >2x/year
Homozygous early complement deficiency (especially C1, C2, and C4) is associated with what?
recurrent bacterial sinopulmonary disease and development of SLE
What are the dreaded organisms that can still thrive in immunosuppressed patients who are receiving very broad-spectrum antibiotics and antifungals?
Fusarium and Aspergillus
1. beefy red nasal mucosa
2. pale blue or “boggy nasal mucosa
1. rhinitis medicamentosa
2. allergic rhinitis
What should you suspect when you see more than one episode of invasive Neisseria?
terminal complement deficiency