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Flashcards in Endocrinology Deck (10):
1

What is the most common cause of cushion's syndrome in a person > 60?

Ectopic ACTH production from small cell lung cancer

2

Is the PAC:PRA ratio low or high with primary aldosteronism? Secondary aldosteronism?

Primary - high (because renin is low)
Secondary like RAS or fibromuscular dysplasia - low (because renin is high)

3

Are FSH/LH increased or decreased in premature ovarian failure and menopause?

Increased due to loss of negative feedback from estrogen

4

What rash is insulin resistance associated with?

Acanthosis nigricans

5

What is the most common cause of exogenous ACTH production in a patient > 60?

small cell lung cancer

6

How does an adrenal tumor present in terms of cortisol and ACTH?

high cortisol and low ACTH

7

How does adrenal hyperplasia present in terms of cortisol and ACTH?

high cortisol and low ACTH

8

How does Cushing disease (pituitary adenoma) present in terms of cortisol and ACTH?

high cortisol and high ACTH
- suppresses with high dose dex test

9

How does an ectopic ACTH-secreting tumor present in terms of cortisol and ACTH?

high cortisol and high ACTH
- fails to suppress with a high dose dex test

10

What is the relationship between thyroid disease and the prolactin levels?

Hypothyroidism causes hyperprolactinemia. Don’t diagnose a prolactinoma until you’ve looked at the thyroid first.