Oncology/Hematology Flashcards Preview

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Flashcards in Oncology/Hematology Deck (15):
1

BRCA1 and BRCA2 increase the risk of what types of cancers?

breast and ovarian

2

What seemingly unrelated disease increases the risk of ovarian cancer by 12%?

Lynch syndrome - hereditary nonpolyposis colon cancer

3

Tumor markers
1. CA-125
2. AFP and hCG are elevated in the this less common classification of cancers?
3. Which type of testicular cancer produces the following?
- AFP
- hCG

1. Ovarian cancer
2. Germ cell cancers
3. nonseminoma

4

When do you see smudge cells?

CLL

5

When do you see teardrop shaped RBCs?

myelofibrosis

6

What is a common complication of hereditary spherocytosis?

Gallstones

7

reed-sternberg cells

hodgkins

8

what is the hairy cell leukemia triad?

pancytopenia (50–75%),
splenomegaly (80–90%), and
inaspirable bone marrow (a dry tap; frequent).

9

Methylmalonic acid (MMA) and homocysteine (HC) in B12 and folate deficiency

Both elevated for B12; HC only for folate deficiency

10

When do you see the t(11:14) translocation?

With Mantle Cell lymphoma

11

Auer rods

AML

12

t (9;22)

Philadelphia chromosome
CML

13

What is the most common leukemia in adults?

AML; CLL is the most common leukemia overall

14

normal PT, elevated PTT, normal CBC, and elevated bleeding time

vWD

15

Which blood malignancy doesn't usually have splenomegaly?

AML