Alzheimer's Flashcards
1
Q
Risk factors of Alzheimer’s disease
A
Age
Genetic
FH of down syndrome
FH of Parkinson’s
Hypothyroidism
Depression
Head trauma
nose picking
2
Q
Alzheimer’s disease pathology
A
Cerebral atrophy
Medial temporal lobe atrophy
fewer smaller neurones
Senile plaques
extra cellular, β-amyloid
Amyloid deposition
in blood vessels
Neuro-fibrillary tangles
intracellular
Acetyl choline: levels reduced
3
Q
Neurobiology of Alzheimer’s disease
A
abnormal amyloid as sheets in plaques
plaque density correlates with cognition
Apolipoprotein E
4
Q
the 5 As of Alzheimer’s disease
A
AMNESIA memory
APHASIA speech
AGNOSIA recognition
APRAXIA doing
Associated behaviours BPSD*
5
Q
Behavioral and Psychological Symptoms of Dementia (BPSD)
A
Psychological
Delusions
Behavioral
