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NE > Anaerobic Gluconeogenesis > Flashcards

Anaerobic Gluconeogenesis Flashcards

1
Q

What happens from pyruvate without oxygenase?

A

Lactate dehydrogenase to lactate

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2
Q

Where does NAD regenerate in aerobic conditions?

A

Mitochondria

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3
Q

what moves nadh and h between cytosol and mitochondria?

A

Shuttle mechanisms

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4
Q

What is the shuttle mechanism?

A

Oxaloacetate to malate to mitochondria to oxaloacetate to aspartate to cytosol

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5
Q

Where is NAD regenerated by in aerobic glycolysis?

A

Glyceraldehyde 3 phosphate

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6
Q

what is fate of lactic acid?

A

Oxygen increase converts back to pyruvate to enter citric acid acycle , in muscle converts back to glucose

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7
Q

what is gluconeogensis?

A

Formation of glucose from non-carbohydrates , occurs in livers

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8
Q

what to triglycerides form?

A

Free fatty acids and glycerol

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9
Q

what is route for glucenogensis?

A

Same as glycolysis but 3 key ezymes :
glucose - 6- phosphate
fructose 1,6,biphosphate
Oxaloacetate

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10
Q

How many atp in total for glucenogensis?

A

6 atp

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11
Q

What happens when energy is high?

A

atp inhibits glycolysis

citrate and acetyl coZ stimulate glucenogensis

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12
Q

what happens when energy is low?

A

amp stimulates glycolysis to produce atp

amp inhibits glucenogensis

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13
Q

What is regulatory hormones of glucose?

A

Fruc-2-6-bip synthesized to PFK2 and broken to FBPase2

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14
Q

What does fruc-2-6-bip do?

A

stimulates glycolysis

inhibit glucenogensis

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15
Q

What does insulin do?

A

inhibits fbpase 2, activate pkf2 - glycolysis stimulated

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16
Q

What does glucagon do?

A

Inhibits pfk2 and activate fbpase 2 stimulation glycolysis low
inhibition glucenogensis reduced

17
Q

What is cori cycle?

A

Lactate produce anaerobic glycolysis in one organ passed to blood via liver

18
Q

what is alanine cycle?

A

in anaerobic conditions muscles make alanine and lactate - shuttled to liver to make glucose

19
Q

where does glucose alanine cycle occur?

A

Skeletal yslce to eliminate nitrogen - less productive and makes urea then has to remove urea , nadh is conserved

NE (17 decks)

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