And the story goes

Question 1

congenital rubella s/s

Answer 1

mom w/ arthritic virus in prego

baby w/ sensorineural hearing loss, cardiac defects, cataracts

ddx by infant IgM

Question 2

congenital varicella s/s

Answer 2

limb hypoplasia
cataracts
skin scarring

Question 3

rapidly progressive glomerulonephritis light microscopy

Answer 3

crescent formation

Question 4

PKU

Answer 4

deficiency of phenylalanine hydroxylase

fair, musty, intellectual disability, eczema

rx: low phenylalanine diet

Question 5

Aldolase B deficiency

Answer 5

hereditary fructose intolerance

NVD, lethargy, sz after introduction of F/V

Question 6

Diabetic nephropathy on light microscopy

Answer 6

hyalinosis of afferent/ efferent arterioles

Question 7

wiskott aldrich

Answer 7

x-linked
thrombocytopenia, eczema, recurrent infections

problem with cytoskeletal regulation

Question 8

wiskott aldrich rx

Answer 8

stem cell transplant

Question 9

________ are effective for the depressive phase of bipolar (not Li)

Answer 9

second generation antipsychotics

Question 10

Imipramine moa

Answer 10

tri-cyclic

Question 11

Citalopram moa

Answer 11

SSRI

Question 12

galacosemia

Answer 12

presents in first days of life after breast milk/ formula

jaundice, hepatomegaly, failure to thrive

Question 13

Congenital hypothyroid s/s

Answer 13

large fontanel
failure to thrive
hypotonia

Question 14

Linear deposits on immunofluorescence

Answer 14

Goodpasture’s

anti-GBM antibody

Question 15

Granular deposits on immunofluorescence

Answer 15

immune-complex

• SLE
• IgA
• post-infectious

Question 16

Two most common causes of amyloidosis

Answer 16

Multiple myeloma- light chain

RA- abnormal protein

Question 17

Hand, foot, and mouth syndrome

Answer 17

caused by coxsackie virus 
vesicular rash (hand foot and mouth)

Question 18

Pertussis and CBC

Answer 18

shows a lymphocytosis

Question 19

Most common cause of ventilator pneumonia

Answer 19

Pseudomonas 
E-coli 
Klebsiella 
MRSA
Strep

Question 20

nitroprusside drip can be concerning for?

Answer 20

cyanide toxicity

• HA
• AMS
• Arrhythmias
• Flushing
• Resp depression

Question 21

In the work up for idiopathic thrombocytopenic purpura, everyone should be tested for ________ infections?

Answer 21

HIV
Hep c

these can mimic the thrombocytopenia

Question 22

Rx for lyme disease in kids under 8

Answer 22

amoxicillin

• also for pregos

Question 23

Bacillary angiomatosis

Answer 23

caused by bartonella

red, friable, firm nodules

Question 24

Most common bug in IV drug use infective endocarditis

Answer 24

S Aureus

*common to embolize to lung and make cavitating lesions

Question 25

Phlegmasia cerulea dolens

Answer 25

severe DVT, extensive thrombotic occlusion sudden severe pain, swelling, cyanosis and edema of the affected limb

Question 26

Felty syndrome CBC

Answer 26

characterized by the triad of RA, splenomegaly, and granulocytopenia. Neutropenia with large granular lymphocytosis (LGL), also known as pseudo-Felty syndrome

Question 27

Thiazides side effects

Answer 27

Blocks NaCl trasport - hypokalemic metabolic alkalosis - hyponatremia - hyperGlycemia, - hyperLipidemia - hyperUricemia, - hyperCalcemia. - sulfa allergy.

Question 28

Polycythemia Vera

Answer 28

bone marrow tumor makes too many red cells (can also do other lines) s/s itching, burning pain in the hands or feet, discoloration of the skin, arthritis

Question 29

Mupirocin

Answer 29

Bactroban | topical antibiotic