Anesthetics Flashcards
(29 cards)
fast onset of LA due to…
high lipid sol + low pKa
Rpoivacain + Epi
Epi has little effect on ropivacain
LA caution in pts…
HTN, PVD, CAD, Cerebebral vascular insuffiency, heart block
Amides caution in pts..
w/ SEVERE HEPTAIC Disease
Prilocaine adverse effect:
methemoglobinemia
voltage and frequency-dependent blockade
LA
Esters Metabolism
PABA, very short acting
Amides Metabolism
Hepatic, CYP450
SE: Hepatic necrosis, hypoxemia
Halothane
Ostwald
Solubility of agent in blood, LARGER = SLOWER
Most common inhalant
Isoflurane
MAC is correlated with…
lipid solubility
Risk: Malignant Hyperthermia
Desflurane
Slow onset and recovery
Halothane
Second gas effect
novel gas introduction causes inc uptake of other gas
dental procedures
NO
SE: Caution w/ Vit B12 deficient pts!
NO!
Irreversibly oxidizes cobalt in Vit B12 deficient pt
NO!
Used alone in short procedures
Thiopental
SE: no antagonist for overdose
Thiopental
“Balanced anesthesia”
Midolezam, for sedation/anxiety
Conscious sedation use BIG GUNS
Fentanyl, Sufentanil
Activates GABA-A receptor
Propofol
Most common parenteral anesthetic
Propofol
