Antiepileptics Flashcards
(57 cards)
1
Q
Phenytoin MOA
A
Na+
2
Q
Lamotrigine, Felbamate MOA
A
Na+ and Glutamate
3
Q
Ethosuximide
A
Ca+
4
Q
Gabapentin
A
Na+, GABA, Ca+
5
Q
Nystagmus
A
Phenytoin
6
Q
Gingival Hyperplasia
A
Phenytoin
7
Q
Rash/SJS
A
Lamotrigine
8
Q
Spina Bifida Tetrogen
A
Valproate
9
Q
Aplastic anemia, hepatoxicity
A
Felbamate
10
Q
Binds to SV2A
A
Lamotrigine
11
Q
Absence seizures
A
Ethosuximide
12
Q
Eliminated by kidneys, PN
A
Gabapentin
13
Q
Tx DM PN
A
Pregabalin
14
Q
Migraine Headache tx
A
Topiramate
15
Q
Possible Retinal Neuropathy
A
Vigabatrin
16
Q
Acute seizures
A
Diazepam
17
Q
leukopenia, hyponatremia
A
carbamazepine
18
Q
trigeminal neuralgia
A
carbamazepine
19
Q
bipolar disorder
A
carbamazepine
20
Q
decrease in bone mineral content
A
phenytoin
21
Q
Focal seizure tx
A
Carbamazepine, Lamotrigine, Leviracetam
22
Q
General, Absent
A
Valproate, Ethosuximide
23
Q
General, Tonic Clonic or Unknown
A
Valproate
24
Q
Zero order kinetics
A
Phenytoin
25
Status Epilepticus (acute seizures)
Diazepam or Lorazepam
26
High Potency Typical
Play Halo while high and get the Flu
Haloperidol
Fluphenazine
27
MOA: Induce EPS, block D2 receptors, increase prolactin
Haloperidol, Fluphenazine (high), Chlorpromazine (low)
28
Tx Schizophrenia
Haloperidol, Fluphenazine
29
More sedative, CNS effect in
Low potency
30
Low Potency Typical antipsychotics
Chlorpromazine
31
risk weight gain, DM, hyperlipidemia
Atypical antipsychotics
32
Major depression tx
ARipiprazole
33
ARipiprazole + Clozapine MOA:
Block 5-HT
34
Clozapine SE
agranulocytosis, need weekly WBC checks
35
Atypical Antipsychotics Mnemonic
Psychoas ARe ZAPped and DONE
| ARipiprazole, cloZAPine, olanZAPine, risperiDONE
36
autism
risperidone
37
anterograde amnesia
benzos
38
Insomnia tx
Flu, Tema... Pam takes Tema-flu for insomnia
39
potentiate GABA inhibition
benzodiazepams!
40
BZD receptor agonist
Zolpidem/Ambien
41
Stimulates benzo receptor
Zolpidem/Ambien
42
BZD/Rescue Antagonist
Flumazenil
43
Partial agonist 5HT-1A receptor
Buspirone
44
Antianxiety, good for truck drivers and workers with high risk jobs need to be awake
Buspirone
45
Short acting
THIO
46
TRIcyclic antidepressants mnemonic
"depressed cause I TRIed but I TRIPT at PRAM"
- itri
- tript
- ipram
47
SE: orthostatic hypotension, sexual dysfunction, sedation, weight gain
tricyclic antidepressants
48
Quinidine-like effects
tricyclic antidepressants
49
mild stimulant + antidepressant
BUPROPRION
50
SSRI's suffix
oxetine
51
SSRI mnemonic
```
"SSRy SER, the PARrot FLUw into the CITy"
SERtraline
PARoxetine
FLUoxetine
CITalopram
```
52
SSRI MOA:
inhibits UPTAKE of 5-HT
53
SE: suicidality
SSRIs
54
eat food containing TYRAMINE... HTN crisis
MAOIs
55
MAOIs mnemonic
"SEL MAyO w/ PHENEL"
SELegiline
PHENELzine
56
hand tremor
lithium
57
Lithium mnemonic
"battery powered VLC"
Valproic Acid
Lamotrigine
Carbamazepine
