Hyperlipidemia drugs Flashcards
(18 cards)
Never take Statins and
Fibrates together, myopathy
Never take this with Statins, will cause toxicity
grapefruit juice
Potentiates coumadin
Lovastatin, simvastatin
suffix monoclonal ABs against PCSK9
-ocumab
use if family hx hypercholesteremia, & ASCVD risk
Bile acid binding resins
SE: GI upset
bine acid binding resins
activates PPAR, reduces TAGs by 50% and increases HDL
Fibrates
CI gallbladder disease
fibrates
hyperTAG
fibrates
potentiates coumadin, indaneiodine
fibrates
inhibits AAC, inhibits sx of fatty acids
niacin
familial hyperlipoproteinemia and LOW HDL
combo therapy Niacin w/ Statin
SE include: flushing, pruritis (cutaneous vasodilation)
Niacin
Contraindicated peptic ulcers
Niacin
SEVERE hyperTAG
Omega
Neurocognitive SE
PCSK9 inhibitors
Hyperglycemia, hyperuricemia
Niacin
decreased mortality in CAD
Statins