Animal Models Flashcards

(15 cards)

1
Q

[T/F] Cancer cell lines may come from transformed cell lines.

A

TRUE

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2
Q

[T/F] A knockout mouse is a mouse wherein certain genes are overexpressed.

A

FALSE

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3
Q

[T/F] In selecting a model organism in metabolic studies, one criterion to consider is the similarity of the organism genome with human.

A

TRUE

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4
Q

[T/F] Cancer cell lines are often derived from actual clinical tumors.

A

TRUE

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5
Q

[T/F] One to consider in metabolic studies is the genetic background of mice that will be used in experiment involving metabolic studies.

A

TRUE

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6
Q

[T/F] Transgenic rats are rats that have foreign DNA inserted into their genome.

A

TRUE

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7
Q

[T/F] Rats are easier to handle and perform procedures than mice since they are large in size.

A

TRUE

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8
Q

[T/F] Passage number is the number of times the cell line has been used in cell assay.

A

FALSE

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9
Q

[T/F] Drosophila are more expensive to maintain than mice.

A

FALSE

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10
Q

[T/F] Ethical guidelines must be followed in using rodents in the laboratory.

A

TRUE

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11
Q

[T/F] In culturingC. elegans, microorganisms likeE. coliis used as their food and nutrient source.

A

TRUE

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12
Q

[T/F] Rats are better organism models compared to rabbits in the study of diabetes.

A

FALSE

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13
Q

[T/F] An albino mice is considered as a general-purpose model.

A

TRUE

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14
Q

[T/F] Rats are better organism model for diabetes, hypertensive, and atheroschlerosis research compared to mice.

A

TRUE

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15
Q

[T/F] Human gut microbiota are rarely used in metabolic studies due to their differences in metabolism.

A

FALSE

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