Anit-arrhythmics Flashcards Preview

Pharmacology > Anit-arrhythmics > Flashcards

Flashcards in Anit-arrhythmics Deck (32):
1

Quinidine (cardioquin)

Class 1A

2

Quinidine (cardioquin) MOA

Binds Activated sodium channels

3

Quinidine (cardioquin) Effects

Broad spectrum. Artial and ventricular arrhythmias

4

Quinidine (cardioquin) Side effects

Torsades due to QT prolongation. Quinidine syncope. Diarrhea.

5

Procainamide (pronestyl)

Class 1A

6

Procainamide (pronestyl) Side Effects

Lupus

7

Lidocaine (xylocaine)

Class 1B

8

Lidocaine (xylocaine) MOA

Binds inactivated sodium channels

9

DOC for ACUTE ventricular arrhythmia

Lidocaine (xylocaine)

10

Lidocaine (xylocaine) Effects

Ventricular arrhythmias with the least negative inotrope effects so useful in CHF

11

Flecainide (tambocor)

Class 1C

12

Flecainide (tambocor) MOA

Blocks all sodium channels. Last Ditch effort.

13

Flecainide (tambocor) adverse effects

pro arrhythmic

14

Beta Blockers

Class II

15

Esmolol Indications

IV only treatment of Acute PSVTs

16

Amiodarone (cordarone)

Class III

17

Amiodarone (cordarone) MOA

Blockes potassium channels. Also blocks sodium channels. Acts as a beta blocker, alpha blocker and CCB

18

DOC for ventricular arrhytmias

Amiodarone (cordarone). Chronic or Acute.

19

Amiodarone (cordarone) Indications

DOC for ventricular arrhythmia but also useful in atrial arrhythmias

20

Amiodarone (cordarone) Adverse effects

Prolongs QT but without torsades. Pulmonary fibrosis. Thyroid dysfunction.

21

Sotalol (betapace)

Class III

22

Sotalol (betapace) MOA

Potassium channel and beta blocker.

23

Sotalol (betapace) Adverse effects

Torsades

24

Calcium Channel Blockers

Class IV. Verapamil and Dilitazem

25

CCB indications

PSVT. Only effective in the atria!

26

CCB adverse effects

Constipation

27

Adenosine

Increased potassium and calcium permeability. Hyperpolarizes the cell. IV only.

28

DOC for acute PSVT

Adenosine

29

Acute PSVT treatment

Adenosine, Esmolol, CCB (IV)

30

Chronic PSVT Treatment

Beta-blocers and CCB (oral)

31

DOC for torsades

Magnesium

32

Potassium MOA

Hyperpolarizes the cell