ANS Pharmacology Flashcards Preview

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Flashcards in ANS Pharmacology Deck (31):
1

Direct-acting sympathomimetics: non-selective

Norepinephrine (α>β1> β2)
Epinephrine (β≥α; dose/route dependent)

2

Direct-acting sympathomimetics: beta 1=beta 2

Isoproterenol

3

Direct-acting sympathomimetics: Beta 1> beta 2

dobutamine

4

Direct-acting sympathomimetics: beta 2 agonists

Albuterol, Salmeterol, Terbutaline

5

Direct-acting sympathomimetics: beta 3 (nonselective) agonists

clenbuterol

used illicitly in US, and dopamine

6

Indirect-acting sympathomimetics

Amphetamine (and cathinone derivatives),
Cocaine,
Dopamine,
Ephedrine,
Tyramine (interacts with MAO Inhibitors primarily)

7

Alpha-adrenergic antagonists: Nonselective

Phentolamine (peripheral)

8

Alpha-adrenergic antagonists: alpha 1 antagonist

prazosin (peripheral)

1a selective: tamsulosin (prostate)

9

Alpha-adrenergic antagonists: alpha 2 antagonist

Yohimbine (central)

10

alpha1 agonist

phenylphrine (direct)

11

alpha2 agonist

clonidine (central)

12

Non-selective beta1 and beta2 antagonists

propanolol
timolol (ocular

13

selective beta 1 antagonists

metoprolol
atenolol
esmolol (short acting

14

beta and alpha antagonist

labetolol
carvedilol

15

Benzodiazepines (GABA agonists):

diazepam

16

diltiazem/verapamil

Calcium channel antagonists (blockers):

cardiac > peripheral

17

Nifedipine/amlodipine

Calcium channel antagonists (blockers):

peripheral > cardiac

18

Vasodilators

Nitroglycerin (venous > arterial)

19

Acetylcholine, Pilocarpine, Muscarine

Muscarinic receptor agonists

20

Nicotine

Nicotinic N receptor agonist

21

Physostigmine

Carbamate (Spontaneously Reversible) Cholinesterase inhibitors

(centrally and peripherally active)

22

Pyridostigmine

Carbamate (Spontaneously Reversible) Cholinesterase inhibitors

(peripherally restricted)

23

Organophosphate Cholinesterase inhibitor (

Malathion (pesticide)
Sarin (warfare agent)

24

Pralidoxime (2PAM)

Cholinesterase reactivator

25

atropine

muscarinic antagonist

26

scopolamine

muscarinic antagonist

27

muscarinic antagonist- ocular

tropicamide

28

muscarinic antagonist- inhaled

ipratropium

29

Succinylcholine

(depolarizing neuromuscular blockade)

30

Non-depolarizing (competitive) nicotinic M receptor antagonists:

d-Tubocurarine (curare)
Vecuronium, Rocuronium

31

Botulinum toxin

Inhibit ACh release at NMJ primarily