Neurotransmitters Flashcards by Hannah Tredway

Q

cocaine

A

blocks dopamine reuptake, leading to enhanced dopamine (pleasure) signals

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Q

amphetamines

A

enter presynaptic neuron, enter dopamine-filled vesicles, allows release of dopamine through pores

increased HR, BP

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Q

ecstasy

A

increases serotonin

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Q

morphine

A

binds to receptors for endorphins

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Q

drug abuse involves

A

reward via mesolimbic pathway

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Q

drug addiction involves

A

activation beyond the mesolimbic pathway

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Q

reward pathway

A

dopamine from VTA to NAc

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Q

nucleus accumbens

A

pleasure area (NAc)

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Q

Ach: Primary postsynaptic effect

A

excitatory

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Q

Glutamate: : Primary postsynaptic effect

A

excitatory

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Q

GABA: : Primary postsynaptic effect

A

inhibitory

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Q

Glycine: Primary postsynaptic effect

A

inhibitory

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Q

Catecholamines: Primary postsynaptic effect

A

modulatory

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Q

Serotonin (5-HT): Primary postsynaptic effect

A

modulatory

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Q

Histamine:: Primary postsynaptic effect

A

modulatory

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Q

endocannabinoids: Primary postsynaptic effect

A

inhibits release of lipids

Q

Ach: Precursor

A

choline + acetyl CoA

Q

Glutamate: Precursor

A

glutamine

Q

GABA: Precursor

A

glutamate

Q

Glycine: Precursor

A

serine

Q

Catecholamines: Precursor

A

tyrosine

Q

Serotonin: Precursor

A

tryptophan

Q

Histamine: Precursor

A

histidine

Q

Ach: Removal mechanism

A

AChEase

Glutamate, GABA, Glycine: Removal mechanism

transporters

Neuropeptides: Removal mechanism

proteases

ACh: Major RLS enzyme

CAT

Glutamate: Major RLS enzyme

glutaminase

Glycine: Major RLS enzyme

phosphoserine

GABA: Major RLS enzyme

GAD

Catecholamines: Major RLS enzyme

tyrosine hydroxylase

Serotonin: Major RLS enzyme

tryptophan hydroxylase

Histamine: Major RLS enzyme

histidine decarboxylase