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Flashcards in Neuro 4 Deck (37):
1

seizure definition

clinical manifestation of abnormal excessive synchronization of a population of neurons

2

epilepsy definition

2 unprovoked seizures greater than 24 hrs apart

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risk of recurrent seizure predictive factors

EEG
seizure etiology

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who has greatest risk of recurrent seizure

symptomatic w/ abnormal EEG
65% after 2 years

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who has least risk of recurrent seizure

idiopathic (normal history/exam)
normal EEG
24% after 2 years

6

when are seizures most likely to occur in a lifetime?

at the extremes of life

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possible seizure triggers

sleep deprivation, alcohol withdrawal, new medications, medication noncompliance

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spike duration

25-70 ms

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sharp wave duration

70-200 ms

10

Jacksonian march is an example of what class of seizure

focal --> simple --> precentral gyrus

11

Fencing: contralateral arm is abducted, externally rotated, elevated and head is deviated
“Flexed arm points to the side of the focus”

SMA seizure

12

insular cortex seizure

Throat paresthesias/tightening/sense of suffocation; salivation; sensory
Autonomic symptoms

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Contralateral deviation of head, eyes, trunk

simple partial seizure- dorsolateral frontal cortex

14

aura

seizure characterized by sensory or psychic disturbance without impaired awareness or other features

15

More or less coordinated adapted involuntary motor activity occurring during the state of clouding of consciousness

automatism -
complex partial seizure

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MRI finding in temporal lobe epilepsy

mesial temporal sclerosis

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frontal lobe epilepsy is difficult to distinguish from what?

PNES

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Brief, clusters, multiple times daily, no postictal period
Stereotyped, hypermotor behavior, i.e. bicycling

Frontal lobe epilepsy

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distinguishing FLE from PNES

NES will not have ictal EEG correlate

20

circadian distribution is a major trait of

myoclonic jerks and GTS's
mostly after morning awakening

21

infantile spasms usually associated with

severe developmental epilepsy syndrome

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hypothalamic nucleus controlling posterior pituitary

paraventricular nucleus

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which pathway controls feeding via oxytocin

parvocellular pathway to the brainstem

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what is damaged in Korsakoff's syndrome

mammillary bodies

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ANS: anterior nucleus of the hypothalamus

parasympathetic

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ANS: posterior nucleus of the hypothalamus

sympathetic

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___ hypothalamus mediates decreases in heat.

anterior

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lesion in the anterior hypothalamus

hyperthermia

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stimulation of anterior hypothalamus

dilation of blood vessels in skin, panting, no shivering

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____hypothalamus mediates heat conservation

posterior

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lesion in posterior hypothalamus

hypothermia in a cold environment

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stimulation of posterior hypothalamus

shivering
constriction of blood vessels in the skin

33

circadian rhythms regulated why which nucleus

suprachiasmatic

34

MPOA lesion in male

no sexual behavior

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lordosis pathways

VMH --> brainstem relays --> lumbar cord

36

gender identification

uncinate to stria terminalis circuit

37

fighting and mating activation in mice

activation of ventrolateral VMH in males