Anti Arrythmics Flashcards Preview

Cardiovascular Drugs > Anti Arrythmics > Flashcards

Flashcards in Anti Arrythmics Deck (14)
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1

What anti arrhythmic drugs are there?

- Adenosine

2

Indications

- Immediate termination of supraventricular tachycardia
- Diagnosis of SVT/VT

3

Contraindications?

- Heart block
- Long QT syndrome
- COPD
- Severe hypotension

4

Cautions?

- Heart transplant

5

What receptors does adenosine work on?

- A1 adenosine receptors

6

What do A1 adenosine receptors open?

- ACh sensitive potassium channels

7

What does the opening of ACh sensitive potassium channels lead to?

- Hyperpolarisation
- Inhibition of calcium channels

8

What does the hyperpolarisation and inhibition of calcium channels cause?

- A brief period of heart block sufficient to terminate the SVT

9

How is adenosine administered?

- Intravenous bolus with increasing dosages until arrhythmia is terminated

10

Besides termination of the arrhythmia, what are the other outcomes of IV bolus adenosine?

- Alternate diagnosis
- Max dose reached

11

Why are adverse reactions from adenosine short lived?

- Very short half life

12

What are the adverse reactions for adenosine?

- Bronchospasm
- Chest pain
- Flushing
- Nausea
- Bradyarrhythmia is possible

13

What drug interacts with adenosine and causes a prolonged anti arrhythmic affect?

- Dipyridamole
- Also if patient is already on anti arrhythmics

14

What should patients be warned about before administering adenosine?

- Effects unpleasant
- Feels like being thumped in the chest