Anti-emetics Flashcards Preview

Clinical Pharm > Anti-emetics > Flashcards

Flashcards in Anti-emetics Deck (54):
1

Zofran dose

4-8 mg

2

Zofran onset

30 min

3

Zofran duration

3-6 hours

4

Zofran concentration

2 mg/ml

5

Zofran class

Serotonin blocker

6

Zofran neurotransmitter

Serotonin

7

Zofran considerations

- first line treatment
- Granisetron and dolasetron

8

Decadron dose

4-10 mg

9

Decadron onset

15-30 min

10

Decadron duration

36-54 hours

11

Decadron concentration

4 mg/ml

12

Decadron class

Glucocorticoid

13

Decadron considerations

- perineal itching
- immunosuppression

14

Scopolamine dose

1.5 mg

15

Scopolamine onset

1-2 min

16

Scopolamine duration

2-8 hours

17

Scopolamine concentration

1.5 mg/patch

18

Scopolamine class

Anticholinergic

19

Scopolamine neurotransmitter

Muscarinic blocker of Acetylcholine

20

Scopolamine considerations

Best effect if applied > 4 hours prior to induction
Watch for anticholinergic side effects
+ HR
+++ CNS
--- secretions

21

Droperidol dose

0.625-1.25 mg

22

Droperidol onset

30 min

23

Droperidol duration

2.5 hours

24

Droperidol concentration

2.5 mg/ml

25

Droperidol class

Butyrophenones

26

Droperidol neurotransmitter

Dopamine

27

Droperidol considerations

Prolongs QT
- Ekg prior, don't give if QT >.440

28

Phenerygan dose

12.5-25 mg

29

Phenergan onset

3-5 min

30

Phenergan concentration

25 mg/ml

31

Phenergan class

Antihistamine

32

Phenergan neurotransmitter

H1/D2/alpha blocking

33

Phenergan considerations

Sedation

34

Reglan dose

10-20 mg

35

Reglan onset

2-5 min

36

Reglan duration

2-4 hours

37

Reglan concentration

5 mg/ml

38

Reglan class

Benzamides

39

Reglan neurotransmitter

Muscarinic blocker of acetylcholine

40

Reglan considerations

Increase gastric motility
CNS depression
Extrapyramidal side effects

41

Aprepitent dose

115-150 mg over 20-30 min

42

Aprepitent onset

10 min

43

Aprepitent duration

9-12 hours

44

Aprepitent concentration

115-150 mg/vial

45

Aprepitent class

Neurokinin 1 antagonist

46

Aprepitent neurotransmitter

Substance P

47

Aprepitent considerations

Used for chemotherapy

48

Benadryl dose

20-50 mg

49

Benadryl onset

15 min

50

Benadryl duration

3-6 hours

51

Benadryl concentration

50 mg/ml

52

Benadryl class

Antihistamine

53

Benadryl neurotransmitter

H1, H2

54

Benadryl considerations

Sedation
Treatment of antiphylaxis