Reversals/anticholinergic agents Flashcards Preview

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Flashcards in Reversals/anticholinergic agents Deck (25):
1

Atropine bolus dose

0.4 mg
0.01 mg/kg

2

Atropine concentration

0.4 mg/ml
1 mg/ml

3

Atropine onset

60-90 seconds

4

Atropine considerations

+++ HR
+ CNS
- secretions

5

Glycopyrrolate bolus dose

0.2-0.4 mg
0.01 mg/kg

6

Glycopyrrolate concentration

0.1 mg/ml

7

Glycopyrrolate onset

2-3 min

8

Glycopyrrolate duration

120-240 minutes

9

Glycopyrrolate considerations

++ HR
No CNS
-- Secretions
Watch for anticholinergic side effects

10

Glycopyrrolate class

Anticholinergic

11

Atropine class

Anticholinergic

12

Nestigmine class

Anticholinesterases

13

Neostigmine dose

0.02-0.08 mg/kg

14

Neostigmine max dose

5 mg

15

Nestigmine concentration

1 mg/ml

16

Neostigmine onset

7 min

17

Neostigmine duration

55-75 min

18

Neostigmine metabolism

50/50 liver/renal

19

Usual neostigmine/glycopyrrolate dose

1 mg neostigmine/0.2 mg glycopyrrolate

20

Edrophonium dose

0.5-1 mg/kg

21

Edrophonium concentration

10 mg/ml

22

Edrophonium onset

1-2 min

23

Edrophonium duration

15-60 min

24

Edrophonium metabolism

70 renal/ 30 hepatic

25

Usual edrophonium/atropine ratio

1 mg edrophonium/0.4 mg atropine