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PHARMACOLOGY > Anti-infective drugs > Flashcards

Anti-infective drugs Flashcards

1
Q

drugs that are designed to act selectively on foreign organisms that have invaded and infected the body

A

ANTI-INFECTIVE AGENTS

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2
Q

2 Spectrum of anti-bacterial agent

A
  • Narrow spectrum anti-infectives
  • Broad-spectrum anti-infectives
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3
Q

These affect only a few bacterial types

A

NARROW SPECTRUM

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4
Q

These affect many bacteria

A

BROAD-SPECTRUM

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5
Q

Examples of narrow-spectrum

A

EARLY PENICILLIN DRUGS

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6
Q

Example of broad spectrum

A

MEROPENEM

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6
Q

Antibiotics that can aggressively cause bacterial death are called ___

A

BACTERICIDAL

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7
Q

Anti-Bacterial agents that interfere with the ability of the cell to reproduce/replicate without killing them are called

A

BACTERIOSTATIC

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8
Q

Broad Spectrum Penicillins (aminopenicillin)

A

 Amoxicillin
 Ampicillin
 Bacampicillin

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8
Q

Narrow spectrum penicillin

A

PENICILLIN G
PENICILLIN V

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9
Q

Penicillinase-resistant Penicillin (anti-staphylococcal penicillin)

A

 Cloxacillin
 Nafcillin
 Methicillin
 Dicloxacillin
 Oxacillin

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10
Q

Extended-Spectrum penicillins (Anti-pseudomonal penicillins)

A

 Carbenicillin
 Mezlocillin
 Piperacillin
 Ticacillin

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11
Q

Beta-lactamase inhibitors

A

 Clavulanic acid
 Sulbactam
 Tazobactam

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12
Q

T/F:

Penicillin and penicillinase-resistant penicillins produce BACTERICIDAL effects by interfering with the ability of susceptible bacteria from biosynthesizing the framework of the cell wall.

A

TRUE

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13
Q

These are indicated for the treatment of streptococcal infections.

A

PENICILLINS

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14
Q

Describe each generations of Cephalosporins (4)

A

1ST GEN: same gram-positive organisms affected by penicillin

2ND GEN: Haemophilus influenza, Entreobacter aerogenes and Nesseria sp. Less effective against gram (+) bacteria

3RD GEN: relatively weak against gram-positive bacteria but more potent against gram-negative bacteria, to include Serratia marcescens.

4TH: resistant gram-negative bacteria

15
Q

This gen of cephalosporin is are largely effective against the same gram-positive organisms affected by penicillin.

A

1ST GEN

16
Q

This gen of cephalosporin are effective against those strains as well as Haemophilus influenza, Entreobacter aerogenes and Nesseria sp. These drugs are less effective against gram positive bacteria

A

2ND GEN

17
Q

This gen of cephalosporin

A
17
Q

This gen of cephalosporin are relatively weak against gram-positive bacteria but more potent against gram-negative bacteria, to include Serratia marcescens.

A

3RD GEN

18
Q

This gen of cephalosporin are developed to fight against the resistant gram-negative bacteria. The first drug is cefepime

A

4TH GEN

PHARMACOLOGY (11 decks)

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