Antilipemic Drugs Flashcards

1
Q

2 primary forms of lipids in the blood

A
  • TRIGLYCERIDE
  • CHOLESTEROL
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

The combination of triglyceride or cholesterol with apolipoprotein

A

LIPOPROTEIN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Types of lipoproteins

A
  • VERY LOW-DENSITY (VDL)
  • LOW -DENSITY (LDL)
  • HIGH -DENSITY (HDL)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

A.k.A “Good cholesterol” ad is responsible for recycling of cholesterol

A

HDL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

A.k.A “Bad cholesterol”

A

LDL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Normal amount of LDL cholesterol

A

<130 mg/dl

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Normal amount of cholesterol

A

<200 mg/dl

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Coronary Heart Disease is caused by (3):

A
  1. Elevated LDL
  2. Elevated triglycerides
  3. Decreased HDL
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Desirable amount of HDL

A

> 60 mg/dl

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Give the antilipemic drugs (6)

A
  1. HMG-CoA reductase inhibitors
  2. Bile acid sequestrants
  3. Niacin
  4. Fibric Acid alternatives
  5. Cholesterol absorption inhibitors
  6. Combination drugs
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Drugs used to lower lipid levels

A

ANTILIPEMIC DRUGS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Increases cell absorption of LDL by blocking the enzyme HMG-CoA reductase

A

HMG-COA REDUCTASE INHIBITORS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

It is used by the liver to produce cholesterol

A

HMG-COA REDUCTASE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Give HMG-CoA Reductase inhibitors

A
  • ATORVASTATIN
  • PRAVASTATIN
  • SIMVASTATIN
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

The first line drug therapy for hypercholesterolemia

A

HMG-COA REDUCTASE INHIBITORS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Give Bile Acid Sequestrants

A
  • Cholestyramine
  • Colestipol
  • Colesevelam
11
Q

Prevent reabsorption of bile acids from small intestine

A

BILE ACID SEQUESTRANTS

12
Q

Also known as fibrates

A

FIBRIC ACID DERIVATIVES

13
Q

Increases activity of lipase which breaks down lipids. Reduces the metabolism or catabolism of cholesterol and triglycerides

A

NIACIN

14
Q

Samples of Fibric Acid Derivatives

A
  • Fenofibrate
  • Gemfibrozil
15
Q

Believed to work by activating lipase, which breaks down cholesterol. Also suppress the release of fatty acid from adipose tissue

A

FIBRIC ACID DERIVATIVES

15
Q

For the treatment of hyperlipidemias

A

FIBRIC ACID DERIVATIVE

16
Q

Inhibits absorption of cholesterol and related sterols from the small intestine

A

EZETIMIBE -CHOLESTEROL ABSORPTION INHIBITOR

17
Q

Herbal product used as antispasmodic, antihypertensive, antiplatelet, lipid reducer

A

GARLIC

17
Q

For atherosclerosis, hypercholesterolemia, GI distress, and menopausal syndrome

A

FLAX

18
Q

Fish oil products used to reduce cholesterol

A

OMEGA 3 Fatty acids

19
Q

Give samples of herbal medicines that lower cholesterol

A
  • GARLIC
  • FLAX
  • OMEGA 3