ANTI-PARASITIC

Question 1

Inhibit Dihydropteroate synthase.

Answer 1

Sulfonamides:
Mafenide, Sulfacetamide, Sulfadiazine, Sulfamethoxazole, Sulfasalazine etc..

Question 2

Inhibit pyrovate-ferrodoxin-oxidoreductase?

Answer 2

Metronidazole

Question 3

Inhibit trypanothione reductase-peroxidase.

Answer 3

Nifurtimox

Question 4

Inhibit ornithine decarboxylase.

Answer 4

Eflornithine

Question 5

Inhibit lanosetrol C14a-demythylase.

Answer 5

Ketoconazole

Question 6

Inhibit glycolic enzymes.

Answer 6

Suramin

Question 7

Inh dihydrofolate reductase-thymidylate synthase.

Answer 7

Antifolates : TMP Trimethylpropan , PMA Phorbol 12-myristate 13 acetate

Question 8

Inh mitochondrial electron transfer?

Answer 8

Chloroquine

Question 9

Inh microtubule polymerization?

Answer 9

Benzimidazoles ( Albendazole)

Question 10

Inh nervous synaptic transmission?

Answer 10

Levamisole
Piperazine
Ivermectin

Question 11

4 aminoquinoline (2)

Answer 11

Chloroquine
Amodiaquine

Question 12

Quinoline methanol

Answer 12

Quinine / Mefloquine

Question 13

8 aminoquinoline

Answer 13

Primaquine

Question 14

Anti folate sulfa?

Answer 14

PMA / Sulfadoxine

Question 15

Anti folate quinone (2)

Answer 15

Atovaquone
Proguanil

Question 16

Tetracycline

Answer 16

Doxycycline

Question 17

Phenanthrene methanol

Answer 17

Halofantrine

Question 18

Amyl alcohol

Answer 18

Lumefantrine

Question 19

Sequiterpine lactone endoperoxides

Answer 19

Artemisinins / Artesunate / Artemether/ Qinghaosu

Question 20

Anti amoebics for asymptomatic? (2)

Answer 20

Diloxanide furoate
Paromomycin

Question 21

Anti amoebics for mild to moderate infection? (4)

Answer 21

Metronidazole/ Tinidazole
Tetracycline/ Erythromycin

Question 22

Anti amoebics for severe intestinal infection? (3)

Answer 22

Metronidazole / Tinidazole
Tetracycline

Question 23

Anti amoebics for hepatic abscess?

Answer 23

Metronidazole/ Tinidazole
Chloroquine

Question 24

Tx Babesiosis?

Answer 24

Clindamycin/ Quinine

Clingy Queen Babe

Question 25

Tx Balantidiasis?

Answer 25

Tetracycline/ Metronidazole Tira Bala sa Metro

Question 26

Tx Gardiasis?

Answer 26

Metronidazole/ Tinidazole Tini ay Guard sa Metro

Question 27

Tx Leishmaniasis?

Answer 27

Na Stibogluconate / AMB/ Ketoconazole

Question 28

Tx Pneumocytosis Jiroveci?

Answer 28

TMP - Sulfa/ Clindamycin - Primaquine

Question 29

Tx for toxoplasmosis in pregnancy?

Answer 29

Spiramycin

Question 30

Tx trichomoniasis?

Answer 30

Metronidazole / Tinidazole

Question 31

Tx of trypanosomiasis?

Answer 31

Suramin/ Benznidazole/ Nifurtimox / Eflornithine Trypanomiasis cruzi Tryp Cruise ship : Sure Benz NinEflor

Question 32

Tx Ascariasis?

Answer 32

Albendazole / Mebendazole

Question 33

Tx trichuriasis?

Answer 33

Mebendazole / Albendazole

Question 34

Tx for necatoriasis / ankylostomiasis?

Answer 34

Mebendazole / Albendazole

Question 35

Tx for enterobiasis?

Answer 35

Mebendazole / Albendazole

Question 36

Tx for trichinosis?

Answer 36

Mebendazole / Albendazole + Steroids

Question 37

Tx for strongyloidiasis?

Answer 37

Ivermectin / Thiabendazole

Question 38

Tx for cutaneous larva migrans?

Answer 38

Albendazole / Ivermectin / Thiabendazole

Question 39

Tx for visceral larva migrans?

Answer 39

Albendazole / Mebendazole

Question 40

Tx for filariasis / loasis?

Answer 40

DEC Diethylcarbamazine

Question 41

Tx for onchocercariasis?

Answer 41

Ivermectin

Question 42

Tx for capillariasis?

Answer 42

Albendazole / Mebendazole

Question 43

Tx for schistosomiasis?

Answer 43

Praziquantel / Oxamniquine

Question 44

Tx for chlonorhiasis?

Answer 44

Praziquantel/ Albendazole Chinese / Oriental Liver Fluke

Question 45

Tx for paragonimiasis?

Answer 45

Praziquantel / Bethionol

Question 46

Tx for fasciolopsiasis?

Answer 46

Praziquantel / Niclosamide Intermediate snail 🐌 intenstinal fluke

Question 47

Tx heterophydiasis?

Answer 47

Praziquantel / Niclosamide

Question 48

Tx for fascioliasis?

Answer 48

Bithionol

Question 49

Tx for taeniasis?

Answer 49

Praziquantel / Niclosamide

Question 50

Tx diphylobothriasis?

Answer 50

Praziquantel / Niclosamide

Question 51

Tx for neurocysticercosis?

Answer 51

Albendazole / Praziquantel

Question 52

Tx for hymenolepsiasis?

Answer 52

Praziquantel / Niclosamide

Question 53

Tx for echinococciasis?

Answer 53

Albendazole

Question 54

Ivermectin clinical uses? (8)

Answer 54

OSA CRASH Onchocerciasis Strongyloidiasis Ascariasis - Trichuriasis -Filariasis Cutaneous larva migrans RADS toxi - reactive airway dysfunctional S. Acne rosacea Scabies Head lice ( humanus capitis)

Question 55

ADR is Mazzoitis reaction : high fever , hypotension, bronchospasm.

Answer 55

Ivermectin

Question 56

Treatment for Mazzoitis Reaction?

Answer 56

Prednisone

Question 57

Rare aderse reaction is corneal opacities.

Answer 57

Ivermectin

Question 58

Quinin induced cinchonism is characterized by? (5)

Answer 58

GI discomfort Headache Tinnitus Vertigo Blurred vision

Question 59

A rare and potentially fatal complication involving Intravascular hemolysis, that can develop in quinine-sensitized individuas?

Answer 59

Blackwater fever

Question 60

Taken on a weekly basis, suitable for prophylaxis in regions where P. Falciparum is not resistant.

Answer 60

Chloroquine

Question 61

Taken on a weekly basis, is recommended in areas where P. falciparum resistance to chloroquine.

Answer 61

Mefloquine

Question 62

Taken on daily basis where in regions with multi-drug resistant malaria. (2)

Answer 62

Doxycycline Malarone ( Atovaquoune + Proguanil)

Question 63

Taken on a daily basis for 14 days as a terminal prophylaxis of P. vivax and P. ovale infections as well as an alternative in primary prevention?

Answer 63

Primaquine