Drugs Of Abuse Flashcards

(48 cards)

1
Q

Drugs that activate G-protein coupled receptors? (4)

A

Opioids
Cannabinoids (THC-CB1) agonist
GHB ( Gamma-hydroxy-butyric acid)
LSD/ Mescaline/ Psilocybin ( 5-HT2)

Tara G! Oppa Cana, Gonna LSD

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2
Q

Drugs that bind to ionitropic R and ion channels? (4)

A

Benzodiazepines
Alcohol - NMDA, GABA, 5-HT, Ach
Nicotine
PCP ( ketamine)

Ion BANK

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3
Q

Drugs that bind transporters of biogenic amines? (3)

A

Cocaine- DAT, SER, NET
Amphetamine - DAT, SERT, NET, VMAT
Ecstasy (MDMA) - DAT, SERT, NET

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4
Q

Blood concentration of Alcohol which causes death?

A

> 500mg/dL

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5
Q

Antidote for Alcohol caused Wernicke- Korsakoffs Syndrome?

A

Vitamin B-1 50mg IM / IV

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6
Q

Antidote for Alcohol poisoning? (8)

A

Fomepizole
Rimonabant
Naltrexone
Ondasetron
Topiramate
Baclofen
Acamprosate
Disulferam

Alcohol poisoning = FRiends Night OuT went BAD

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7
Q

Alcohol concentration : Sedation , high, slow reaction

A

50-100mg/ dL

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8
Q

Alcohol concentration : Impaired motor, slurred speach, ataxia

A

100-200mg/dL

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9
Q

Alcohol concentration : Emesis, Stupor

A

200-300mg/dL

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10
Q

Alcohol concentration : Coma

A

300-400mg/dL

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11
Q

Alcohol concentration : Respiratory Depression , Death

A

> 400mg/dL

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12
Q

Symptoms of Alcohol withdrawal syndrome for the first 3-4 days? (8)

A

Tremors
Anxiety
Hallucinations
Palpitations
Anorexia
Insomnia
Nausea
Seizures

True AlcoHol PAINS during withdrawal

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13
Q

Symptoms of Alcohol withdrawal syndrome after 3-4 days?

A

Delirium Tremers :
Tachycardia
HPN
LG fever
Tremor
Diaphoresis
Delirium
Agitation

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14
Q

Agent that cause snowstorm visual, hcho breath found in gasoline additive, xerox, solvents?

A

Methanol

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15
Q

Antidote for Methanol poisoning?

A

Ethanol
Fomepizole
Hemodialysis

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16
Q

Antidote for ethylene glycol poisoning?

A

Ethanol
Fomepizole
Hemodialysis

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17
Q

Antidote for Opioids poisoning?
Opioids :
Heroine
Morphine
Codone
Meperidine ( pethidine)

A

Naltrexone 100-150mg/ d 3x / week

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18
Q

Poisoning caused Goose flesh / cold- turkey ?

A

Opioids

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19
Q

Other names of Cocaine?

A

Coca
Freud
Crack
Speed
Heroine ( Speed ball)

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20
Q

Other names for Methamphetamine?

A

Speed
MDMA
Ecstasy
Raves
Cathinone
Run / Rush - orgasmic - like
Ice - base crystals

21
Q

Treatment for Methamphetamine overdose / toxicity?

A

Chlorpromazine
Diazepam
Baclofen - GABA-A

22
Q

Other names for Marijuana?

A

MJ
Cannabis
Hemp
Grass
Hashish
THC

23
Q

Volatile gas aka Poppers?

24
Q

Volatile gas aka as Headshops?

25
Volatile gas found in rugby, shoe polish, thinner, glue, rubber cement?
N2O ( Nitrous Oxide)
26
Old drug for nicotine?
Mecamylamine
27
A-2 agonist indicated for smoking cessation?
Clonidine
28
Partial nicotinic acetylcholine receptor (A4B2) agonist, banned due to suicidal / psychotic tendencies?
Varenicline
29
DOC for Depression( Unicyclic) which Inhibits dopamine receptors?
Bupropion
30
Drugs that causes hyperkalemia? (3)
Digitalis B- blockers K sparing diuretics
31
Drugs that causes hypokalemia? (4)
Thiazides Loop diuretics Xanthines Beta agonists
32
Drugs causes HAGMA? ( 5)
Metformin ASA Alcohol INH Fe Hug Ma MAAIn Friend
33
Drugs which causes prolonged QT ? (3)
TAD LITHIUM QUINIDINE Too Liit Queen - prolonged Cutie
34
Drugs that cause widened QRS?
Quinidine TAD
35
Drugs that cause AV Block?
Digitalis
36
Acetylcysteine is the antidote for what poisoning ? (3)
Acetaminophen Cyclophosphamide Watusi
37
Atropine is the antidote for what poisoning ? (4)
OP Carbamates Mushroom ACE Inh
38
NaHCO3 is the antidote for what poisoning ? (2)
TAD Quinidine
39
Deferoxamine is the antidote for what poisoning ? (2)
Fe Al
40
Esmolol is the antidote for what poisoning ? (2)
Theophylline Metaproterenol
41
Ethanol is the antidote for what poisoning ? (2)
Methanol E. glycol
42
Flumazenil is the antidote for what poisoning ?
Benzodiazepines
43
Glucagon is the antidote for what poisoning ?
Beta blockers
44
Naltrexone is the antidote for what poisoning ? (2)
Opioids Alcohol
45
Naloxone is the antidote for what poisoning ?
Acute Opioid overdose
46
Treatment for CO poisoning?
Hyperbaric O2
47
Antidote for atropine poisoning?
Physostigmine Neostigmine
48
Antidote fore ACE Inh poisoning?
Pralidoxime