Toxicology

Question 1

Bluish irritant gas produced i. Air and water purification devices and in electrical fields that may cause irritation / dryness of the mucous membranes.

Answer 1

Ozone

Question 2

Antidote to methanol or ethylene glycol ?

Answer 2

Fomepizole

Question 3

Antidote to theophylline ?

Answer 3

Esmolol

Question 4

Chelating agent for arsenic , mercury, lead.

Answer 4

Dimercaprol

Question 5

A patient with sweet garlicky odor in breath and stools may have poisoned with?

Answer 5

Arsenic

Question 6

Minamata disease is associated with?

Answer 6

Organic mercury poisoning

Question 7

Transverse bands on the nails in chronic arsenic poisoning

Answer 7

Mees lines

Question 8

Ingestion of flakes in paint may lead to toxicity with?

Answer 8

Lead

Question 9

Activated charcoal is effective for? (10)

Answer 9

1. Amitriptyline
2. Barbiturate
3. Carbamazepine
4. Digitalis
5. Glycosides
6. Phencyclidine
7. Propoxyphene
8. Theophylline
9. Tricyclic Antidepressants
10. Valproic acid
    (ABCD GPPT TV)

Question 10

Activated charcoal is not effective for? (9)

Answer 10

1. Potassium
2. Lithium
3. Alcohols
4. Acids
5. Carbamazepine
6. Cyanide
7. Corrosive
8. Ethylene glycol
9. Solvents
   PLAACCCES

Question 11

Hemodialysis is effective for?

Answer 11

1. Carbamazepine
2. Ethylene glycol
3. Lithium
4. Methanol
5. Metformin
6. Phenobarbital
7. Salicylate
8. Theophylline
9. Valproic acid

Question 12

Hemodialysis is not effective for?

Answer 12

1. Amphetamines
2. Antidepressants
3. Antipsychotics
4. Benzodiazepines
5. Calcium channel blockers
6. Digoxin
7. Metoprolol
8. Propranolol
9. Opioids

(AAABCD OPM)

Question 13

Tetradotoxin block or inhibit?

Answer 13

Voltage - gated Sodium Channels

Question 14

Tetraethylammonium (TEA) Poison found in ovaries of puffer fish block or inhibit?

Answer 14

Potassium Voltage -gated channels inhibiting action potential generation

Question 15

Conotoxin block or inhibit?

Answer 15

Calcium voltage-gated channel

Question 16

Lead toxicity treatment? (3)

Answer 16

Chelation Challenge Test
- IM Dimercaprol ( Universal antidote)
- Ca Na EDTA - parenteral
- Succimer PO

Question 17

Substance that caused toxicity through batteries, Tv, Plating, Plastics , Smelters?

Answer 17

Cadmium

Question 18

Substance that caused toxicity through dental appliances, alloys, ceramics?

Answer 18

Beryllium

Question 19

Used for aircraft disinfectant ?

Answer 19

Pyrethrum

Question 20

Treatment for pyrethrum toxicity? (3)

Answer 20

Ivermectin
Pentobarbital
Mephenesin

Question 21

Cause anti-knock additives in gasoline?

Answer 21

Organic lead

Question 22

Heavy metals that causes Aldrich mees lines in nails?

Answer 22

Inorganic Arsenic

Question 23

Heavy metals that binds to sulfhydril and PO4 also found in fowlers solution?

Answer 23

Inorganic Arsenic

Question 24

Heavy metals that is used as Chemical warfare?

Answer 24

Inorganic Arsenic

Question 25

Heavy metals that causes stocking glove dysesthesia?

Answer 25

Arsenic

Question 26

Affects children who plays toys , quicksilver, cinnabar ore, dental amalgam, apparatus, antiseptic?

Answer 26

Mercury

Question 27

Heavy metals that causes tremors, erethism ( explosive anger), acrodynia, miliarial rash when chronically exposed?

Answer 27

Mercury

Question 28

Heavy metals that causes parkinsonism-like symptoms?

Answer 28

Manganese

Question 29

Heavy metals that is used in terrorism “dirty bomb”?

Answer 29

Ur , Ce, Th

Question 30

Treatment for smoking cessation obesity?

Answer 30

Remonabant - moa cannabinoid CB-1 receptor antagonist

Question 31

Antidote for atropine toxicity?

Answer 31

Neostigmine

Question 32

Antidote for red tide : Shellfish Neurotoxins Saxitoxin Tetradotoxin Brachiotoxin Conotoxin

Answer 32

Methoxamine

Question 33

Antidoto for watusi ( phosphorus)

Answer 33

Ca Mg Acetylcysteine

Question 35

Phytonadione is the antidote for what poisoning ? (3)

Answer 35

Warfarin Watusi Rat poison

Question 36

What is the antidote for Nifedipine poisoning?

Answer 36

CaCl2

Question 37

Ca gluconate and MgSo4 are the antidote for what poisoning ? (3)

Answer 37

Organochlorines Phosphate ( Watusi) F

Question 38

Pyridoxine is the antidote for what poisoning ? (2)

Answer 38

INH H2S

Question 39

D-penicillamine is the antidote for what poisoning ? (3)

Answer 39

Cu Au Hg

Question 40

Na-Ca EDTA is the antidote for what poisoning ? (4)

Answer 40

Pb Co Mn Zn

Question 41

Diphenhydramine is the antidote for what poisoning ?

Answer 41

Phenothiazines

Question 42

Succimer is the antidote for what poisoning ? (3)

Answer 42

Pb Hg Sb

Question 43

Trientine is the antidote for what poisoning ?

Answer 43

Cu

Question 44

Unithol is the antidote for what poisoning ? (2)

Answer 44

Hg As inorganic

Question 45

Methemoglobinemia treatment? (2)

Answer 45

Vitamin C B-12

Question 46

Dimercaprol (BAL) is the antidote for what poisoning ? (4)

Answer 46

As Pb Hg Au

Question 47

Identify the drug that causes Toxic syndrome: HPN AND SEROTONIN SYNDROME

Answer 47

MAOIs

Question 48

Identify the drug that causes Toxic syndrome: SEXUAL, SEIZURES AND SEROTONIN SYNDROME

Answer 48

SSRIs

Question 49

Identify the drug that causes Toxic syndrome: SEIZURES

Answer 49

Bupropion

Question 50

Identify the drug that causes Toxic syndrome: QT PROLONGATION , NMS

Answer 50

D-2 BLOCKERS

Question 51

Identify the drug that causes Toxic syndrome: RESPIRATORY ALKALOSIS METABOLIC ACIDOSIS HPN

Answer 51

ASA

Question 52

Identify the drug that causes Toxic syndrome: HYPOTENSION BRADYCARDIA QRS BLOCK

Answer 52

BETA BLOCKER

Question 53

Antidote for B blocker toxicity?

Answer 53

Glucagon

Question 54

Identify the drug that causes Toxic syndrome: SLOW AV NODE HYPOTENSION HIGH INSULIN

Answer 54

Calcium Channel Blocker

Question 55

Antidote for CCB toxicity?

Answer 55

Glucagon Lipid emulsion

Question 56

Identify the drug that causes Toxic syndrome: HYPOTENSION TACHYCARDIA HYPOKALEMIA HYPERGLYCEMIA

Answer 56

Theophylline

Question 57

Medication used to prevent nephrotoxicity from platinum compounds used in cancer chemotherapy?

Answer 57

Amifostine

Question 58

Functions as iron chelator , used to mitigate cardiotoxicity associated with anthracyclines?

Answer 58

Dexrazoxine

Question 59

A sulfhydril compound binds to acrolein a toxic metabolite of cyclophosphamide/ ifofosfamide , and employed to prevent hemorrhagic cystitis resulting from chemotherapeutic agents?

Answer 59

Mesna

Question 60

Rapid Iv administration of Deferoxamine can cause?

Answer 60

Hypotensive Shock

Question 61

Flumazenil will reverse the effects of what drugs?

Answer 61

FADE Alprazolam Diazepam Eszopiclone