Antibiotics Flashcards
what microbes are susceptible to penicillin
mostly gram positive:
- Penicillin-susceptible S. pneumoniae
- Groups A, B, C, G streptococci
- Viridans group streptococci
- Enterococcus
+ others
what is Benzathine PCN used for
Treponema pallidum (syphilis) or other STD
which gram negative bacteria does PCN cover
Neiserria meningiditis
penicillinase resistant penicillins
Nafcillin, dicloxacillin, oxacillin
penicillinase resistant penicillins cover what
mostly MSSA
- can be used for strep infections
aminopenicillins types
Ampicillin, amoxicillin
amino penicillin covers what
Gram negative:
- Salmonella
- Shigella
- Some E. coli
- Some H. influenza
- Proteus mirabilis
in addition to the normal gram positive penicillin coverage
anti-pseudomonal penicillin name
piperacillin-tazobactam – Zosyn
anti-pseudomonas penicillin coverage
Gram negative:
- Pseudomonas
- Salmonella
- Shigella
- E. coli
- H influenza
- Enterobacter
- Klebsiella penumoniae
- Serratia marcescens
in addition to the normal gram positive penicillin coverage
beta lactamase inhibitor combo antibiotics
augmentin
unsyn
zosyn
avicaz
Zerbaxa
combo antibiotic coverage
gram positive: MSSA
gram negative:
- Bacteroides
- E. coli
- Klebsiella
- Proteus
1st generation cephalosporins
Cefazolin: IV (Ancef)
Cephalexin: PO (Keflex)
Cefadroxil: PO (Duracef)
1st gen cephalosporin coverage
Best activity against gram positive
- MSSA
- PCN-susceptible S. pneumonia
- Group A, B, C, G strep
- Viridans group strep
gram negatives: UTI microbes
- E. coli
- Klebsiella pneumonia
- Proteus mirabilis
2nd gen cephalosporins
Cefuroxime: IV and PO Zinacef, and PO Ceftin
Cefoxitin: IV Mefoxin
Cefaclor: PO Ceclor
2nd gen cephalosporin coverage
gram positive normal cephalosporin coverage
gram negative:
- E. coli
- Proteus mirabilis
- H influenza
- Neisseria
- Moraxella catarrhalis
some anaerobe coverage:
- Bacteroides
- Clostridium (not c diff)
