Anticoagulants Flashcards Preview

2 Cardiovascular > Anticoagulants > Flashcards

Flashcards in Anticoagulants Deck (11):
1

What does a thrombus in the venous circulation consist of...

Why are anticoagulants no good for arterial curculation

Fibrin web enmeshed with platelets and red cells

...in the arterial circulation thrombus is mainly platelets and little fibrin

2

Which has a longer duration of action... LMWH or UFH

LMWH

3

What is the advantage of UFH

Shorter duration of action so use in high risk as effect rapidly terminated by stopping transfusion

4

LWWH : name three

Dalteparin
Enoxaparin
Tinzaparin

5

Why are LMWH preferred for prevention of DVT (3)

No monitoring
Lower risk of heparin induced thrombocytopenia
Once daily admin is usually fine

6

What is a role of LMWH in cancer

Dalteparin and Tinzaparin licenced for extended prophylaxis of DVT in patients with solid tumours (6 months)

7

Role of her paring in maintaining the patently of peripheral venous catheters?

Apparently sodium 0.9% is as effective

For arterial and central catheters the role is unclear
According to the BNF...

8

Fondaparinux mode of action

Synthethic pentasacarride that inhibits activated factor X

9

Asinine contraindicated under what age? Except....

16
When specifically indicated such as kwasaki syndrome or high risk of stroke

10

Interactions with aspirin (4)

NSAIDs -s/e
SSRI & venlafaxine- bleed
Methotrexate - reduced renal excretion of methotrexate
Acetozolamide (diuretic)

11

Symptoms of aspirin overdose

Tinnitus
Hyperventilation
Deafness
Vasodilation
Sweating