Flashcards in Anticoagulants Deck (11):
What does a thrombus in the venous circulation consist of...
Why are anticoagulants no good for arterial curculation
Fibrin web enmeshed with platelets and red cells
...in the arterial circulation thrombus is mainly platelets and little fibrin
Which has a longer duration of action... LMWH or UFH
What is the advantage of UFH
Shorter duration of action so use in high risk as effect rapidly terminated by stopping transfusion
LWWH : name three
Why are LMWH preferred for prevention of DVT (3)
Lower risk of heparin induced thrombocytopenia
Once daily admin is usually fine
What is a role of LMWH in cancer
Dalteparin and Tinzaparin licenced for extended prophylaxis of DVT in patients with solid tumours (6 months)
Role of her paring in maintaining the patently of peripheral venous catheters?
Apparently sodium 0.9% is as effective
For arterial and central catheters the role is unclear
According to the BNF...
Fondaparinux mode of action
Synthethic pentasacarride that inhibits activated factor X
Asinine contraindicated under what age? Except....
When specifically indicated such as kwasaki syndrome or high risk of stroke
Interactions with aspirin (4)
SSRI & venlafaxine- bleed
Methotrexate - reduced renal excretion of methotrexate