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Flashcards in Duiretics Deck (20)
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1
Q

which diuretics cause potassium loss (2)

A

thiazide like and loop

greater risk with thiazide

2
Q

potassium loss caused by diuretics is a particular problem in patients also taking

A

cardiac glycocisdes (and those with CVD)

3
Q

why is hypokalaemia caused by diuretics a particuluar problem in liver disease

A

may percipitate encephalopathy

4
Q

what is in co-amilozide

A

amiloride (k sparing)
and
hydrocholthiazide (thiazide like)

5
Q

which thiazide like diuretics are now preferred for treatment of hypertension

A
indapamide
chlortalidone (may be given on alt days to control odema)
6
Q

what conditions might be exacerbated by loop diuretics (3)

A

diabetes (but hypergylcaemia is more likely with thiazide like)
gout
urinary retention in enlarged prostate

7
Q

what class is furosemide

A

loop

8
Q

what class is bumetanide

A

loop

9
Q

what class is indapmide

A

thiazide like

10
Q

how long do duitretic actions of bumetanide and furosemide last

A

up to 6 hours - so can be BD

11
Q

what class is amiloride

A

K sparing

12
Q

K sparing diuretics must not be given with

A
k supplements
(neither should aldosterone antagonists)
13
Q

what class is spironolactone

A

aldosterone antagonists (which means it is also K sparing)

14
Q

what are first and second line diuretics to be used in cirrhosis of the liver

A

spironolactone and then furosemide

15
Q

what class is manitol

A

osmotic - used for cerbral oedema and raised intraoccular pressure

16
Q

acetazolamide is what type of drug..

A

carbonic anhydrase inhibitor (used for altitude sickness) - weak diuretic effect

17
Q

what are the affects of thiazide like diuretics on elctrolytes and uric acid and glucose

A

all do down except calcium goes up

uric acid and glucose go up

18
Q

what are the affects of loop diuretics on elctrolytes and uric acid and glucose

A

all do down

uric acid and glucose (not as much as thiazides) go up

19
Q

what are the affects of K sparinge diuretics on elctrolytes (1)

A

k goes up

20
Q

what are the affects of aldosterone antagonists diuretics on elctrolytes (3)

A

k goes up
na goes down
uric acid goes up