Antipsychotics & Depression Flashcards

(28 cards)

1
Q

Citalopram

A

Starting Dose: 20mg
Depression: 20-40mg
OCD: 40-60mg

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2
Q

Escitalopram

A

Starting: 10mg
Depression & Anxiety:10-20mg
OCD: 20mg

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3
Q

Fluoxetine

A

Starting: 20mg
Depression: 20-40mg
Anxiety: 80mg
OCD: 40-60

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4
Q

Paroxetine

A

Starting: 20mg
Depression: 20-40mg
Anxiety: 20-50mg
OCD: 40-60mg

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5
Q

Sertraline

A

Starting: 50mg
Depression: 50-150mg
Anxiety: 25-200mg
OCD: 200mg

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6
Q

Mirtazapine

A

Starting: 15mg QHS
Target: 15-45mg

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7
Q

Duloxetine

A

Starting: 30-60mg
Target: 60 mg

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8
Q

Venlafaxine

A

Starting: 37.5-75mg
Depression: 75-150mg
Anxiety: 37.5-225

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9
Q

Bupropion XL and IR

A

Starting: 150mg (divided doses for IR)
Target: 150-300 mg
Max: 450mg

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10
Q

Bupropion SR

A

Starting: 200mg
Target: 150-300 mg
Max: 300-400mg

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11
Q

Haloperidol

A

Starting: 1-15mg/day
Target: 2-20mg
Max: 100mg

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12
Q

Risperidone

A

Starting: 1-2mg/day
Target: 2-8mg/day
Max: 16 mg

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13
Q

Paliperidone

A

Starting: 6mg/day
Target: 6-12mg/day
Max: 12mg

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14
Q

Olanzapine

A

Starting: 5-10mg/day
Target: 10-20mg/day
Max: 20 mg (oral)

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15
Q

Aripiprazole

A

Starting: 10mg/day
Target: 10-30mg/day

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16
Q

Brexpiprazole

A

Starting: 1 mg/day
Target: 2-4mg/day

17
Q

Lithium

A

Starting: 300mg BID
Typical dosing: 900-2400mg/day

Target serum levels: 0.8-1.2 mEq/L (acute), 0.6-1.2 (maintenance)

18
Q

Valproate

A

15-20mg/kg/day- in divided doses (rounded to nearest 250)

Max: 60mg/kg/day

Switching from IR or DR to ER- increase dose by 20%

19
Q

Not recommended in panic disorder

A

Propranolol
buspirone
tiagabine
trazodone
carbamazepine

20
Q

Not recommended in acute mania

A

lamotrigine
lumateperone
lurasidone

21
Q

Not recommended in acute depression in bipolar

A

haloperidol
paliperidone
risperidone
ziprasidone

22
Q

EPS

A

High:
some “done medications”
High potency FGAs
D2 partial agonists- akathisia

Low:
-most “pine” medications

23
Q

Anticholinergic

A

pines (except asenapine)
-clozapine highest

low potency FGAs

24
Q

Hypotension

A

Clozapine> risperidone
low potency FGAs
older pines

25
Sedation
high: asenapine, quietiapine, cloazpine, olanzapine low potency FGAs low: D2 partial agonists, lumateperone, high potency FGAs
26
Weight gain Antipsychotics
high: clozapine, olanzapine low: lurasidone, ziprasidone
27
Clozapine
5 black box warnings: -agranulocytosis -myocarditis -hypotension -seizures -mortality in dementia patients Starting dose: 12.5mg bid, increasing 25mg /day until desired efficacy Target: 300-430 mg in divided doses Max: 900mg/day
28
Weight gain antidepressants
Mirtazapine, paroxetine, TCAs