PCEUT EXAM 2 Flashcards by Madeline Jensen

Q

Vedotin

A

MMAE
inhibit microtubules

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Q

emantasine

A

DM1 and DM4
Inhibit microtubules

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Q

govitecan

A

SN-38
Topoisomerase inhibitors

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Q

Deruxtecan

A

DXd
Topoisomerase inhibitors

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Q

Calicheamicin

A

bacterial toxin that causes DNA strand breaks

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Q

PMD dimers (pyrrolobenzodiazepines)

A

DNA alkylation

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Q

Brentuximab Vedotin

A

IgG1 antibody for CD30 and MMAE

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Q

Trastuzumab Emtansine

A

HER2 antibody and DM1

NON-CLEAVABLE

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Q

Sacituzumab Govitecan

A

Trop-2 antibody
SN-38

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Q

Enfortumab Vedotin

A

Nectin-4
MMAE

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Q

Trastuzumab
Deruxtecan

A

HER2
DXd

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Q

Mirvetuximab Soravtansine

A

Folate receptor-alpha
DM4

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Q

Ipilimumab

A

binds CTLA-4

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Q

Pembrolizumab

A

anti PD-1

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Q

Atezolizumab

A

anti PD-L1

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