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Exam 1 Flashcards

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1
Q

AOM 1st line therapy

A

No antibiotics within 30 days- Amoxicillin 90mg/kg divided q12h

Antibiotics within 30 days or severe symptoms- Amox-clav

Alternative: cefdinir 14mg/kg/day divided q12h

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2
Q

AOM Failed Therapy

A

Ceftriaxone 50mg/kg/day x3days

or

Clindamycin 30-40mg/kg/day divided q8h AND/OR cephalosporin

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3
Q

AOM Treatment Length

A

Under 2 yrs: 10 days
2-5yrs: 7 days
Over 6 yrs: 5-7 days
Adult: 10 days

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4
Q

ABS 1st line therapy

A

Amox-clav: 875/125- 1t q12h

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5
Q

ABS 2nd line therapy

A

Amox-clav: 1000/62.5- 2t q12h

Doxycycline: 100 mg bid

Clindamycin: 300-450 mg tid
AND
Cefpodoxime: 200mg bid

Levofloxacin: 750 mg daily

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6
Q

ABS Treatment Duration

A

Normal: 5-7 days
Severe: 7-10 days

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7
Q

Empiric Treatment of Meningitis

A

**1month-50yrs:
Ceftriaxone 2g IV q12h +
Vancomycin: 15-20mg/kg IV q8-12 hrs (2g loading dose and 1.25g q8-12hrs)

**Over 50yrs or complications: **
Ceftriaxone +
Vancomycin
+Ampicillin 2gIV q4h

Alternative:
Meropenem: 2g IV q8h

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8
Q

CAP, low risk, no comorbidities

A

Amoxicillin: 1g tid OR
Doxycycline: 100mg bid OR
Azithromycin: 500 mg x1 day, then 250mg x4days

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9
Q

CAP, low risk with comorbidities

A

Amox-clav: 875/125 1t bid OR
Cefpodoxime: 200mg bid OR
Cefuroxime: 500 mg bid

PLUS

Doxycycline 100mg bid OR
Azithromycin 500mg x1 day, then 250mg x4 days

OR JUST
Levofloxacin 750mg qd

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10
Q

CAP, high risk, not severe

A

Beta-lactam (ceftriaxone 1-2g IV q24h)

PLUS
Macrolide (azithromycin 500mg IV q24h)

OR
Doxycycline 100mg bid

OR FLUOROQUINOLONE MONOTHERAPY:
Moxifloxacin 400mg qd
Levofloxacin 750mg qd

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11
Q

CAP, high risk, severe

A

Beta-lactam (ceftriaxone 1-2g IV q24h)

PLUS
Azithromycin (500mg IV q24h)
OR
Fluoroquinolone

NO MONOTHERAPY

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12
Q

Amoxicillin AOM Dose

A

90mg/kg/day divided q12h

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13
Q

Cefdinir AOM Dose

A

14mg/kg/day divided q12h

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14
Q

Ceftriaxone AOM Dose

A

50mg/kg/day x3days

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15
Q

Clindamycin AOM Dose

A

30-40mg/kg/day divided q8h

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16
Q

Azithromycin AOM Dose

A

10mg/kg on first day
5mg/kg on days 2-5

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17
Q

Amox-Clav ABS Dose

A

875/125 1t bid
or
1000/62.5 2t bid

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18
Q

Doxycycline Dose

A

100mg bid

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19
Q

Clindamycin ABS Dose

A

300-450mg q8h

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20
Q

Levofloxacin ABS Dose

A

750mg qd

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21
Q

Ceftriaxone Meningitis

A

Ceftriaxone 2g IV q12h

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22
Q

Vancomycin Meningitis

A

Vancomycin: 15-20mg/kg IV q8-12 hrs (2g loading dose and 1.25g q8-12hrs)

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23
Q

Meropenem Meningitis

A

2g IV q8h

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24
Q

Ampicillin Meningitis

A

Ampicillin 2g IV q4h

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25
CAP Amoxicillin
1g tid
26
Cefpodoxime CAP
200mg bid
27
Cefuroxime
500mg bid
28
CAP Ceftriaxone
1-2g q24h
29
Severe CAP Azithromycin
500mg IV q24h
30
Moxifloxacin CAP
400mg qd
31
Purulent Cellulitis
TMP-SMX: 2 DS Tablets q12h Doxycycline: 100mg q12h Vancomycin
32
Non-purulent cellulitis
Cephalexin: 500 mg q6h Dicloxacillin: 500mg q6h Clindamycin: 300mg q8h
33
Erysipelas
Penicillin G 1-2mu IV q6h
34
Necrotizing Fasciitis
Piperacillin-tazobactam: 4.5g IV over 30mins then 3.375g IV over 4 hrs q8h Linezolid: 600mg IV q12h
35
HAP/VAP ,no mssa
Piperacillin-tazobactam Cefepime Levofloxacin Imipenem/meropenem
36
HAP/VAP, mrsa
Piperacillin-tazobactam cefepime/ceftazidime levofloxacin/ciprofloxacin imipenem/meropenem aztreonam AND Vancomycin Linezolid
37
HAP/VAP with risk factors
piperacillin-tazobactam cefepime/ceftazidime imipenem/meropenem aztreonam AND Levofloxacin/ciprofloxacin amikacin/gentamicin/tobramycolistin/polymixin B AND Vancomycin linezolid
38
Piperacillin-tazobactam dose
4.5g IV x1, then 3.375g IV q8h
39
Cefepime dose HAP
2g IV q8h
40
Ceftazidime HAP
2g IV q8h
41
Imipenem HAP
500 mg q6h
42
Meropenem HAP
1g q8h
43
Amikacin HAP
15-20mg/kg q24h
44
Gentamicin HAP
7mg/kg q24h
45
Tobramycin HAP
7mg/kg q24h
46
Ciprofloxacin HAP
400mg q8h
47
Levofloxacin HAP
750mg IV q24h
48
Colistin HAP
5mg/kg IV x1, then 2.5mg/kg q12h
49
Polymixin B HAP
2.5-3mg/kg/day divided in 2 doses
50
Linezolid HAP
600mg q12h
51
Necrotizing Fasciitis if clostridium
penicillin G 3-4mu IV q4h linezolid if not clostridium, discontinue linezolid
52
Uncomplicated UTI
Nitrofurantoin: 100mg bid x5days TMP-SMX: 160/800 bid x3days Fosfomycin: 3g single dose
53
Complicated UTI
Levofloxacin: 750mg qd x5days Ciprofloxacin: 500mg q12h x 7-14days
54
Acute pyelonephritis
levofloxacin: 750mg IV/PO q24h x5-7days ciprofloxacin: 400mg IV (500mg PO) q12h x5-7days
55
Acute pyelonephritis and FQ resistance
Ceftriaxone 1g IV q24h x 10days
56
Acute pyelonephritis resistant organism risk
cefepime 2g IV q8h meropenem 1g IV q8h ertapenem 1g IV q24
57
Gonorrhea
<150kg: ceftriaxone 500mg IM x1 >150kg: ceftriaxone 500mg IM x1 +(if chlamydia can't be ruled out) doxycycline 100mg bid x7days or azithromycin 1g po x1day (if pregnant)
58
Chlamydia
doxycycline: 100mg bid x7days Alternatives: azithromycin 1g po x1 levofloxacin 500mg po q24h x7days
59
syphilis
Benzathine penicillin G 2.4 mu IM x1 Late latent/tertiary: Benzathine penicillin G 2.4 mu IM qwk x3 weeks Neurosyphilis: benzathine penicillin G 3-4 mu IM q4h x10-14days
60
Herpes
first clinical episode: -acyclovir 400mg PO tid x7-10 days -famciclovir 250mg PO tid x7-10 days -valacyclovir 1g PO bid x7-10 days Recurrent infection: -aciclovir 400mg bid -valacyclovir 500mg/1g qd -famiciclovir 250mg bid

Therapeutics (18 decks)

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