Antivirals Flashcards Preview

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Flashcards in Antivirals Deck (5):
1

Tx for Herpes (most types)

Aciclovir:
Guanosine analogue, blocks viral DNA extension.
(CMV doesn't have the thymidine kinase so it doesn't work.)

2

Tx for CMV

Ganciclovir.
SFX: BM suppression.
2nd: Foscarnet.
3rd: Cidofovir for retinitis.

3

Antivirals for Influenza

Amantadine (A only) (H1N1 now resistant).
NA inh: Oseltamavir, Zanamivir, Sialic acid.

4

Tx for Hep B

Pegylated interferon alpha 2a,
Entecavir, (viral Pol inh)
Tenofovir (RTI).

5

Tx for Hep C

Peglyated interferon alpha 2b,
Ribavirin (RNA nu analogue; haemolytic anaemia)