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Flashcards in Micro Deck (10):
1

RTIs in HIV (3)

Pneumocystis jirovecii (PCP)
TB
Cryptococcus neoformans

2

RTI in neutropaenia

Fungi - Aspergillus spp.

3

RTI in BMT

Aspergillus + CMV

4

RTIs after splenectomy

Encapsulated:
H influenzae, S pneumoniae, N meninigitidis

5

Organisms in bacterial (acute) meningitis

- Neisseria meningitidis (G-)
- Strep pneumoniae (G+)
Neonates: GI flora - GBS, Listeria, E coli.
Elderly: GBS, Listeria, TB (subacute).

6

Organisms in viral (aseptic) meningitis

- Enterovirus eg. coxsackie
- Mumps
- HSV2 + echovirus in babies.

7

Organism in fungal meninigitis

Cryptococcus neoformans - chronic

8

Bacterial meningitis -
Aetiology, RF, Presentation

Systemic spread from mucosa or local from #skull.
RF: complement def, hyposlenism.
N men: hypogammaglobulinaemia,
S pneum: Alcoholic immune def, pneumonia, entry #.
Presents: Headache, vomiting, photophobia, irritable, fever, rash.

9

Bacterial meningitis -
Dx and Tx

Dx: Clincal, blood cultures, serum Ag, EDTA-PCR, throat swab.
CSF: ^WCC, ^protein, low gluose.
Tx: Resuscitate. Ceftriaxone + corticosteroids + amicillin for Listeria.

10

Interpreting CSF

Polymorphs: bacteria.
Low glucose: active bacteria.
Mononuclear cells: viruses.
High protein and Mononuclear cells: TB or cryptococcus.