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Flashcards in Aortic Arch derivatives Deck (41):
1

Artery of 1st aortic arch

Maxillary artery (branch of external carotid)

2

Artery of 2nd aortic arch

Stapedial artery and hyoid artery

3

Artery of 3rd aortic arch

Common Carotid artery and proximal part of internal Carotid artery

4

Artery of 4th aortic arch

Left - aortic arch
Right - proximal part of right subclavian artery

5

Artery of 6th aortic arch

Proximal part of pulmonary arteries and (on LEFT) ductus arteriosus

6

a. What are branchial clefts derived from?
b. Branchial arches?
c. Branchial pouches?

a. Ectoderm
b. Mesoderm and neural crest
c. endoderm

7

What does 1st branchial cleft become?

External auditory meatus

8

What do 2nd through 4th branchial clefts become?

Form temporary cervical sinuses --> obliterated by proliferation of 2nd arch mesenchyme

9

Cause of branchial cleft cyst within lateral neck

Persistent cervical sinus (2nd-4th clefts)

10

Nerve of 1st branchial arch

CN V2 and V3 (chew)

11

Nerve of 2nd branchial arch

CN VII (Facial expression) (smile)

12

Nerve of 3rd branchial arch

CN IX (Stylo-pharyngeus) (think swallow styl-ishly)

13

Nerve of 4th branchial arch

CN X (superior laryngeal branch) - swallow

14

Nerve of 6th branchial arch

CN X (recurrent laryngeal branch) - speak

15

Muscles of 1st arch

Muscles of mastication (temporalis, masseter, lateral and medial pterygoids), Mylohyoid, anterior belly of digastric tensor tympani, tensor veli palatini

16

Muscles of 2nd arch

Muscles of facial expression; Stapedius, Stylohyoid, PlatySma, posterior belly of digastric

17

Muscles of 3rd arch

Stylopharyngeus (think stylopharyngeus innervated by glossopharyngeal)

18

Muscles of 4th arch

Most pharyngeal constrictors; cricothyroid; levator veli palatini

19

Muscles of 6th arch

ALL intrinsic muscles of larynx EXCEPT cricothyroid

20

Cartilage of 1st arch

Meckel cartilage
Mandible
Malleus, Incus
Spheno-Mandibular ligament

21

Cartilage of 2nd arch

Reichert cartilage: Stapes, Styloid process, lesser horn of hyoid, Stylohyoid ligament

22

Cartilage of 3rd arch

Greater horn of hyoid

23

Cartilage of 4th and 6th arch

Thyroid, cricoid, arytenoids, corniculate, cuneiform

24

1st pouch derivatives

Middle ear cavity, eustachian tube, mastoid air cells

25

2nd pouch derivatives

Epithelial lining of palatine tonsil

26

3rd pouch derivatives

Dorsal wings - inferior parathyroids
Ventral wings - thymus

27

4th pouch derivatives

Dorsal wings - superior parathyroids

28

Mutation in germline RET (neural crest cells)

MEN2A --> pheochromocytoma, parathyroid tumor, medullary thyroid cancer

29

Failure of fusion of maxillary and medial nasal processes

cleft lip (formation of primary palate)

30

Failure of fusion of 2 lateral palatine processes or failure of fusion of lateral palatine processes with nasal septum and/or median palatine process

cleft palate

31

a. Paramesonephric duct becomes...
b. Mesonephric duct becomes...

a. Mullerian duct = female genitalia
b. Wolffian duct = male genitalia

32

Which cells secrete Mullein Inhibitory factor?

Sertoli cells

33

What does paramesonephric duct develop into?

Fallopian tubes, uterus, UPPER portion of vagina, lower portion of urogenital sinus

34

Primary amenorrhea in female with fully developed secondary sexual characteristics (functional ovaries)

Mullerian agenesis (no uterus)

35

What does mesonephric duct become? (SEED)

Seminal vesicle
Epididymis
Ejaculatory duct
Ductus deferens

36

Gartner duct

Remnant of mesonephric duct in females

37

What forms male external genital and prostate?

DHT

38

Male internal genitalia
Ambiguous external genitalia until puberty

5 alpha reductase deficiency (testosterone levels increased at puberty)

39

Male and female internal genitalia
Male external genitalia

No sertoli cells or lack of mullerian inhibitory factor

40

Bicornuate uterus

Incomplete fusion of Mullerian ducts

41

Uterus didelphys

Complete failure of fusion --> double uterus, vagina and cervix