(Arcanobacterium) Trueperella and Actinobaculum Flashcards Preview

RUSVM Bacteriology Gram Positives > (Arcanobacterium) Trueperella and Actinobaculum > Flashcards

Flashcards in (Arcanobacterium) Trueperella and Actinobaculum Deck (17)
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1

Describe the bacterium: Trueperella

Gram positive, catalase negative, pleomorphic, facultative anaerobe, non-spore forming, non-motile, non-capsulated, capnophilic

2

Arcanobacterium- Acid fast? Hemolysis?

No mycolic acids so acid fast NEGATIVE. BETA hemolytic

3

Arcanobacterium - description

Gram positive, anaerobic. Variable hemolysis

4

When I say summer mastitis, you say....

Trueperella pyogenes!

5

Cows - Pyogranulomatous mastitis

Trueperella pyogenes

6

Summer Mastitis pathogenesis & virulence factors

Physical/microbial barrier broken--> adhesion--> Neuramidases expose receptors, aids binding--> Proteases, DNAases help spread. - Pyolysin O=pore-forming, damages host cell

7

Most important virulence factors of arcanobacterium

Pyolysin O (PLO) - Neuraminidase - DNAase - Proteases

8

When I say liver abscesses in cattle, you say...

A. pyogenes (though could also be Fusobacterium necrophorum)

9

A. pyogenes in bovine

**Liver abscesses**, mastitis, endometritis, abortion, endocarditis

10

A. pyogenes in caprine (less important)

Mastitis

11

A. pyogenes in porcine (less important)

Pneumonia, septic arthritis, endocarditis

12

A. pyogenes in poultry (less important)

Osteomyelitis, nephritis

13

A. pyogenes in ovine (less important)

Pneumonia, abortion, endometritis

14

Boars- commensal diphtheroid prepucial mucosa, sexually transmitted to sows, cystitis & pyelonephritis, Dysuria, hematuria, death from renal failure. Urease = main virulence factor

Actinobaculum suis. (Similar to C. renale in bovine)

15

When I say STD of swine with cystitis/ pyelonephritis, you say...

Actinobaculum suis

16

Dx test for Actinobaculum suis

Urease positive! - CNA agar growth (selective media)

17

Case Study - Nubian goats with disseminated infection. First cases of abscess within the bone marrow

Arcanobacterium pyogenes in a goat