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RUSVM Bacteriology Gram Positives > Listeria > Flashcards

Flashcards in Listeria Deck (16)
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1

Listeria - Descriptive statement

Gram positive, *motile* *peritrichous flagella*, coccoid rod shaped, *non acid fast* catalase +, oxidase -, non-spore forming, Facultative anaerobe

2

Listeria CAMP positive with which species?

L. monocytogenes with Staph aureus - L. invanovii with R. equi

3

Listeria intracellular/extracellular?

Facultative intracellular in macrophages

4

Listeria Pathogenesis

Intestinal & CNS routes (via neural sheath of trigeminal nerve)

5

Listeria Virulence factors

**ActA** (hijack actin cytoskeleton for intracellular movement) - *Internalins* (adhesion & entry into cell) ***Listeriolysin O*** (main facor, pore-forming)

6

Listeria are associated with what type of food in domestic animals? What seasons most common

Silage - Silage diseases is classic. Winter & spring most

7

Listeria in ruminants

"M-A-C-E" - Mastitis - Abortion - Conjunctivitis- Encephalitis (Circling Diseases, perivascular cuffing seen on histo)

8

When I tell you a cow is circling, you might say

Listeria! -Likely death in 2-3 days

9

If perivascular cuffing is seen in ruminant CNS histology, you might think...

Listeria!

10

If a fetus is aborted late-term and appears macerated, or delivered weak and moribund, you think...

Listeria!

11

What type of bacteria is risky in *unpasteurized milk*, due to it's subclinical infection of cows?

Listeria!

12

Listeria in birds

Myocardial necrosis - degenerative & serofibrinous pericarditis

13

Myocardial necrosis, degenerative & serofibrinous pericarditis in birds

Listeria!

14

Listeria in horses

Septicemia in neonates

15

Listeria in chinchillas

*Particularly susceptible*

16

Listeria in humans

Often food-bourne: Unpasteurized milk, cold cuts! Can cause abortions in pregnant ladies - 5th most common cause of bacterial meningitis