Asissted conception Flashcards
(22 cards)
What is ACT?
Assisted conception treatment- Any treatment which involves gametes outside the body
Other indications for ACT?
Cancer patients fertility preservation
Same sex couples
Treatment to avoid transmission of blood born viruses between patients
Pre treatment checklist (10)
Alcohol Smoking Weight Folic acid Rubella Cervical smear Occupational hazards Drugs Screen for BBV Assess ovarian reserve
What is IUI?
Prepared semen inserted into uterine cavity around time of ovulation
Indications for IUI?
Unexplained infertility
Mild-moderate endometriosis
Mild male infertility
Indications for IVF?
Unexplained Pelvic disease Anovulatory infertility Male infertility Others
What is down regulation in IVF?
Synthetic gonadotrophin releasing hormone, reduces cancellation from ovulation, allows precise timing of oocyte recovery by using HCG trigger
Side effects of down regulation?
Hot flushes and mood swings
Nasal irritation
Headaches
What is ovarian stimulation?
Gonadotrophin hormone containing either synthetic or urinary gonadotrophins
S/c injection
Causes follicular development
Side effects of Ovarian stimulation?
Mild allergic reaction
Ovarian hyper stimulation syndrome
What is the purpose of an action scan?
Adequate response to FSH or abandon treatment
Assess for OHSS
Plan timing of HCG injection
Purpose of HCG injection?
Mimics LH causing resumption of meiosis in oocyte, 36 hours before oocyte recovery
Sperm sample abstinence period?
72 hours
Assesment of sperm sample?
Volume
Density
Motility
Progression
Risks of oocyte collection procedure?
Bleeding
Infection
Failure
Function of embryologist after harvest?
Search through follicualr fluid
Identify eggs and surrounding cells
Collect them an culture
Incubate at 37 degrees
Name of a 16 cell human embryo?
Morula
Which day is transfer and cryopreservation usually carried out?
5
What is given to the mother after embryo transfer?
Progesterone suppositories
Indication for Intra cytoplasmic sperm injection?
Severe male infertility
Previous failed fertilisation with IVF
Preimplantation genetic diagnosis
ICSI process?
Each egg is stripped
Sperm immobilised
Single sperm injected
Incubate at 37 overnight
What is OHSS?
Enlarged ovaries- excess follicles
Abdo pain, nausea, diarrhoea, SOB