Male infertility

Question 1

Which hormone and factor cause the development of male internal genital tract?

Answer 1

Testosterone and Mullerian inhibiting factor

Question 2

Which duct is responsible for develpment of the male genital tract?

Answer 2

Wolffian ducts

Question 3

Which duct is responsible for the development of the female genital tract/

Answer 3

Mullerian ducts

Question 4

Features of androgen insensitivity syndrome?

Answer 4

X linked recesive
46XY
Testis develop but do not descend
Androgen induction of wolfiann duct does not occur, mullerian inhibition does occur

Question 5

What is the mechanism of descent and raising the testes?

Answer 5

Nervous reflexes trigger dartos muscle contraction in scrotal sac to raise or lower tesits

Question 6

Which cells are responsible for testosterone production in the testes?

Answer 6

Leydig cells

Question 7

Role of Sertoli cells?

Answer 7

Blood-testes barrier
Provide nutrients
Phagocytosis
Secrete seminiferous tubule fluid
Secrete androgen binding globulin
Secrete inhibin and activin hormones

Question 8

Which hormones are responsible for spermatogenesis?

Answer 8

Testosterone

FSH

Question 9

Which hormone is responsible for decreased secretion of FSH?

Answer 9

Inhibin

Question 10

Which hormone is responsible for testosterone secretion

Answer 10

LH

Question 11

What effect does testosterone have on GnRH and LH?

Answer 11

Decrease

Question 12

What effect does GnRH have on FSH and LH

Answer 12

Stimulates release

Question 13

What effect does LH have on Leydig cells?

Answer 13

Regulates testosterone secretion

Question 14

What effect does FSH have on Sertoli cells

Answer 14

Enhances spermogenesis

Question 15

Epidydimis and vas deferens function?

Answer 15

Exit route from testes to urethra
Concentrate and store sperm
Sperm maturation

Question 16

Semina vesicles function?

Answer 16

Semen into ejaculatory duct
Supply fructose
Secrete prostaglandins
Secrete fibrinogen

Question 17

Function of prostate gland?

Answer 17

Produces alkaline fluid

Produces clotting enzymes

Question 18

Function of bulbourethral gland?

Answer 18

Secrete mucus to act as lubricant

Question 19

Nerve control of erection?

Answer 19

Parasympathetic (Point)

Question 20

Nerve control of ejaculation?

Answer 20

Sympathetic (shoot)

Question 21

Common causes of male infertility?

Answer 21

Idiopathic
CF
infection

Question 22

Endocrine causes of infertility?

Answer 22

Pit tumours
hypothalmic
Thyroid
Diabetes
CAH
Steroid abuse

Question 23

Examination in infertile male?

Answer 23

General exam
Genital exam
test. volume (Orchidometer)
Presence of vas def and epididymis
Penis

Question 24

What is measured in investigation of sperm?

Answer 24

Volume
Density
Motility
Progression
Morphology

Question 25

What is intra uterine insemination?

Answer 25

Semen is prepared and inseminated into uterine cavity around ovulation Bascially concentration of sperm

Question 26

What is intracytoplasmic sperm injection?

Answer 26

Sperm injected into stripped oocyte obtained during IVF

Question 27

What is surgical sperm aspiration?

Answer 27

Sperm aspirated surgically then injected into oocyte