Aspergillus Fumigatus-Asparagus Farm

Question 1

What is the state of catalase in Aspergillus Fumigatus

Answer 1

Catalase positive

Question 2

What is the product produced by Aspergillus Flavus associated with cancer

Answer 2

Aflatoxin

Question 3

What cancer is aflatoxin produced by Aspergillus Flavus associated with

Answer 3

Hepatocellular carcinoma

Question 4

Histologically, what are the characteristics of Aspergillus Fumigatus

Answer 4

Branching at an acute angle with septations. Contains candiophore fruiting bodies

Question 5

What form of Aspergillus Fumigatus is infectious

Answer 5

Conidiophores are inhaled

Question 6

What is the method of transmission for Aspergillus Fumigatus

Answer 6

Inhalation of fruiting conidiophores

Question 7

What are the three forms of infection caused by Aspergillus Fumigatus

Answer 7

1) Allergic bronchopulmonary aspergillus (ABPA)
2) Aspergillomas
3) Angioinvasive aspergillosis

Question 8

What type of hypersensitivity is Aspergillus Fumigatus causing allergic bronchopulmonary aspergillus (ABPA)

Answer 8

Type 1

Question 9

Which antibody level will be elevated in Aspergillus Fumigatus caused allergic bronchopulmonary aspergillus (ABPA)

Answer 9

IgE

Question 10

What are the conditions caused by Aspergillus Fumigatus induced allergic bronchopulmonary aspergillus (ABPA)

Answer 10

Wheezing (asthma), fever, migratory pulmonary infiltrate

Question 11

What infection is generally predisposing patients to Aspergillus Fumigatus casing aspergillomas

Answer 11

Cavity causing diseases, highly associated with TB

Question 12

What are the characteristics of Aspergillus Fumigatus caused aspergillomas

Answer 12

Gravity dependent fungus balls, so they are found at the bottom of the cavity

Question 13

Which patient population is prone to Aspergillus Fumigatus causing angioinvasive aspergillosis

Answer 13

Immunocompromised patients, particularly pts with neutropenia from leukemia or lymphoma

Question 14

What are the clinical effects of Aspergillus Fumigatus causing angioinvasive aspergillosis

Answer 14

Invades blood vessels and tissues

-Causes kidney failure, endocarditis, nasal sinus invasion and key ring enhancing lesions in brain

Question 15

Which CT finding is indicative of Aspergillus Fumigatus causing angioinvasive aspergillosis

Answer 15

Ring enhancing lesions in the brain

Question 16

What is the treatment for milf Aspergillus Fumigatus infections

Answer 16

Voriconazole

Question 17

What is the treatment for serious and angioinvasive Aspergillus Fumigatus infection

Answer 17

Amphotericin B