Parvovirus B19-Bombs Away

Question 1

What is the nucleic acid in Parvovirus B19

Answer 1

Single stranded DNA virus

Question 2

What is the state of envelope in Parvovirus B19

Answer 2

No viral envelope present

Question 3

What is the smallest DNA virus

Answer 3

Parvovirus B19

Question 4

How is the Parvovirus B19 transmitted

Answer 4

Respiratory droplets, vertical transmission

Question 5

What illnesses are caused by Parvovirus B19

Answer 5

Fifths disease aka slapped cheek disease aka erythema infectiosum

Question 6

What is the clinical order of presentation of Parvovirus B19

Answer 6

• Starts with a low grade fever
• Develops the slapped cheek rash
• Then travels down the body as a lacy reticular rash pattern

Question 7

In adults, which group commonly gets Parvovirus B19 and what are the clinical presentations

Answer 7

Normally school teachers and those who are commonly around kids. They will have joint pain, arthritis, and soreness

Question 8

Which group with Parvovirus B19 is at a higher risk of developing aplastic anemia

Answer 8

Sickle cell patients

Question 9

Sickle celled patients with Parvovirus B19 are at a higher risk of developing what

Answer 9

Aplastic anemia

Question 10

What would the bone marrow of a patient with aplastic anemia look like

Answer 10

A cob webbed appearance due to only hepatocytes remaining due to the other cells not being present

Question 11

What is the clinical affect of pregnant mothers being infected with Parvovirus B19

Answer 11

Hydrops fetalis, leading to severe edema and death