Neisseria Meningitides- Death On Campus Flashcards
(16 cards)
What is the result of plating Neisseria on Thayer Martin Agar
Aka VPN agar and selective for Neisseria
What is the environment that Neisseria Meningitides is commonly seen
Close quarters with a lot of people present, such as college dorms, military recruits
What is the method of transmission for Neisseria Meningitides
Respiratory droplets
What is unique about Neisseria Meningitides that separates it
Ferments maltose
Where does Neisseria Meningitides colonize first
Oropharynx and then transmitted
Which strains of Neisseria Meningitides are included in the vaccine
A,C,D but not B
What strain of Neisseria Meningitides is most commonly the cause of infections
Strain B, because not included in the vaccine
What is the common stem that will point to Neisseria Meningitides
College student with meningitis
Which conditions predisposes patient to Neisseria Meningitides infection
Sickle celled and asplenic patients who are prone to capsulated bacteria
What is the virulent factor that causes the pathogenesis of Neisseria Meningitides
LOS (lipooligiosaccharde) in the capsule, which comes off during replication and causes an immune response
What is the result of LOS coming off of Neisseria Meningitides envelopes
Vasodilation leading to leaky vessels, hypovolemia, and shock
What is a characteristic sign seen on the skin that can indicate Neisseria Meningitides infection
Petechial rash leading to thrombocytopenia and DIC
What is Waterhouse fritter syndrome
In order to counteract the hypovolemia, there is max vasoconstriction. This leads to adrenal infarct and subsequent loss of SNS
What bacteria can cause Waterhouse Fritter syndrome
Neisseria Meningitides
What is the treatment for Neisseria Meningitides
3rd generation cephalosporin (ceftriaxone) which must be able to cross the BBB
What is given as propholaxis to those individuals in close contact with the sick individual
Rifampin
