Trypanosoma Brucei Gambiense And Rhodesiense-Prince Bruce Flashcards

(10 cards)

1
Q

What illness does Trypanosoma Brucei Gambiense And Rhodesiense cause

A

African sleeping sickness

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2
Q

What is the location Trypanosoma Brucei Gambiense And Rhodesiense is comonly seen

A

Africa

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3
Q

What is the vector for Trypanosoma Brucei Gambiense And Rhodesiense

A

Tsetse fly

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4
Q

What is the path of Trypanosoma Brucei Gambiense And Rhodesiense when it enters the blood

A

Enters the blood and travels to the cervical and axillary LN

-Can also penetrate the CNS and spinal fluid

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5
Q

What are the clinical presentations of Trypanosoma Brucei Gambiense And Rhodesiense

A

Cervical and axillary lymphadenopathy
Coma
Recurrent fevers

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6
Q

What is the method of diagnosis of Trypanosoma Brucei Gambiense And Rhodesiense

A

Blood smear will contain trypomastogotes

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7
Q

What is the virulence factor of Trypanosoma Brucei Gambiense And Rhodesiense

A

Antigenic variation due to constantly changing glycoprotein coats, hence the cause of recurrent fevers

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8
Q

What is the status of mobility for Trypanosoma Brucei Gambiense And Rhodesiense

A

Motile with a single flagella

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9
Q

What is the treatment for the CNS symptoms caused by Trypanosoma Brucei Gambiense And Rhodesiense

A

Melarsoprol

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10
Q

What is the treatment for the peripheral blood symptoms seen in Trypanosoma Brucei Gambiense And Rhodesiense

A

Suramin

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