Asthma Drugs

Question 1

Name the short-acting agonists of β2 adrenoceptors. (2)

Answer 1

• Salbutamol

- Terbutaline

Question 2

What are the effects of Salbutamol and Terbutaline?

Answer 2

• Bronchodilation

- Can cause tachycardia

Question 3

Name the long-acting agonists of β2 adrenoceptors. (2)

Answer 3

• Formoterol

- Salmeterol

Question 4

What are the actions of Theophylline in the body?

Answer 4

• Antagonist for adenosine receptors.
• Non-selective
  phosphodiesterase inhibitor.

Question 5

What is the effect of Theophylline?

Answer 5

• Reduces heart rate

- Reduces the breakdown of cAMP.

Question 6

Ipratropium is a competitive antagonist for which receptor?

Answer 6

muscarinic acetylcholine receptors (mAChR)

Question 7

Name the competitive antagonists at leukotriene receptors. (2)

Answer 7

• Montelukast

- Zafirlukast

Question 8

What are the effects of Montelukast

and Zafirlukast?

Answer 8

• Reduce smooth muscle contraction and mucus secretion

- Reduce exercise and aspirin induced asthma.

Question 9

How does the hormone Glucocorticoid act on the body?

Answer 9

Nuclear hormone receptors

Question 10

What is the effects of Glucocorticoids?

Answer 10

Suppresses inflammation and immune responses to asthma.