Cardiac Dysrhythmia Drugs Flashcards
How do Amiodarone and Sotalol act?
By blocking potassium channels.
What are the effects of Amiodarone and Sotalol?
- Prolonging of action potential and refractory periods.
- Heart rate slows
What receptors do the L isomer of Sotalol act on?
Cardiac β1 adrenoceptors as an antagonist.
How does Adenosin act?
- By activating potassium channels.
- This slows the heart rate.
What is Digoxin used for?
- Slow AV node conduction
- Improves ventricular filling.
Name the β-blockers. (2)
- Propanolol
- Atenolol
What are the effects of the β-blockers?
- Slows the discharge rate of the SA node.
- Slows conduction through the AV node.
- Useful in preventing arrhythmias after a heart attack.
Name the sodium channel blockers. (4)
- Lidocaine
- Disopyramide
- Procainamide
- Flecainide
How do the sodium channel blockers act?
- Block sodium channels
- Reducing firing of action potentials
- Reducing heart rate
What are the risks of using Lidocaine?
Can cause convulsions or a coma if it enters the CNS
What is the risk of using Disopyramide, Procainamide, and Flecainide?
If used after heart attacks, they increase the risk of sudden death.
Which channels does Verapamil act on and how?
Blocks L-type voltage-gated calcium channels.
What effect does Verapamil have?
- Slows SA and AV node conduction.
- Slowing heart rate.
When should Verapamil not be taken?
With Ventricular dysrhythmias and Wolff Parkinson-White
syndrome patients.
