Autism Spectrum Disorder

Question 1

Chromosome ideogram depicting inferred what?

Answer 1

copy number variations found in 196 individuals with ASD

Question 2

What is the main cause of ASD?

Answer 2

CNV’s. WIth 10-20% of ASD cases believed to be the result of submicroscopic deletions and duplications

Question 3

Convergent ASD pathways (8)

Answer 3

Synaptic gene transcription and translation pathway

Neural cell adhesion molecules

Ubiquitination pathway

Scaffolding protein in synapse

Ion channel proteins

Neuron transmitter reporter

Chromatin remodeling