Auto-antibodies 1 Flashcards by H JP

Q

Ank spond

A

HLA B27

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Q

p-ANCA

A

Churg Strauss (eosinophilic granulomatosis)
Microscopic polyangitis

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Q

c-ANCA

A

Wegener’s/ granulomatosis polyangitis

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Q

p-ANCA other associations (4)

A

UC
PSC
Crohn’s
Anti-GBM

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Q

HLA B51

A

Behcets

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Q

Behcets

A

HLA B51

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Q

Dermatomyositis (2)

A

ANA (80%)
Anti Jo1 Anti Mi 2 (30%)

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Q

Drug induced lupus
+ve (2) and -ve

A

ANA 100% +ve
anti-histone 90%
dsDNA negative

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Q

HLA A3

A

Haemochromatosis

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Q

HLA B27 (3)

A

Ank spond
RA
Acute anterior uveitis

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Q

HLA DQ2/DQ8

A

Coeliac

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Q

anti-Jo1 anti-Mi2

A

Polymyositis/ dermatomyositis

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Q

Anti Ro La + ANA (70%) (50% RhF)

A

Sjogren’s

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Q

SLE (3)

A

ANA
anti-dsDNA
anti-Smith

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Q

Systemic sclerosis
Antibodies
Diffuse
Limited

A

ANA 90%
Diffuse - scl-70 antibodies
Limited - anti-centromere

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Q

Scl 70 antibodies

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A

Diffuse systemic sclerosis

Q

Anti-centromere

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A

Limited systemic sclerosis

Q

Anti-histone

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A

Drug induced SLE

Q

Tower of 2

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A

15 months

Q

Tower of 3

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A

18 months

Q

Tower of 6

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A

2 years

Q

Tower of 9

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A

3 years

Q

Line

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A

2

Q

Circle

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A

3

Cross

4

Square and triangle

5

Scribble

18 months

200 words

2.5 years

Short sentences Identifies colours Counts to 10

3yo

Asks why, when, how

4yo

Asks what who

3yo

Turns towards sound

3 months

Double syllables

6 months

Mama and dada

9 months

Responds to name

12 months

Combines 2 words in sentences

2yo