Gynaecology 1 Flashcards

(53 cards)

1
Q

Amenorrhoea definition
Primary

A

Primary: failure to establish menses by 15yo with secondary sexual characteristics or 13yo if no secondary sexual characteristics

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2
Q

Amenorrhoea definition
Secondary

A

Cessation of menses for 3-6 months in women with previously normal and regular menses
Or 6-12 months in women with previous oligomenorrhoea

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3
Q

Postpartum hypopituitarism caused by necrosis of the pituitary gland.

A

Sheehan’s

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4
Q

An acquired condition where scar tissue (adhesions) form inside your uterus

A

Asherman’s syndrome

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5
Q

Investigations for amenorrhoea

A

FBC, U+E, Coeliacs, TFTs, prolactin, androgen levels, oestradiol, gonadotrophins

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6
Q

Amenorrhoea screen
Raised gonadotrophins versus low

A

Raised = ovarian cause
Low = hypothalamic cause

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7
Q

Bleeding in the first trimester
Who should be referred to an early pregnancy assessment service?

A

> =6 weeks

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8
Q

How is bleeding for <6K managed?

A

If no pain or RF for ectopic then to return if bleeding develops
Repeat pregnancy test in 7-10days and return if positive
If negative then = miscarriage

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9
Q

Most common type of cervical ca?

A

SCC 80%
Adeno 20%

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10
Q

HPV serotypes that can increase risk of cervical ca (3)

A

16,18, 33

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11
Q

Cervical ca RF (8)

A

HPV
Smoking
HIV
Early first intercourse
Many sexual partners
High parity
Lower socioeconomic status
COCP

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12
Q

Cervical screening ages:

A

25-49 - every 3 years (Scotland every 5 years)
50-64 - every 5 years

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13
Q

Cervical screening in pregnancy

A

Delay for 3 months post partum unless missed screening or previous abnormal smears

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14
Q

Screening explained/ results explained
HPV negative =

A

HPV negative - return to normal recall

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15
Q

Screening explained/ results explained
HPV +ve =

A

Cytology if normal then repeat test at 12 months

Cytology if abnormal then for colposcopy

If inadequate then repeat sample within 3 months, if x2 inadequate then colposcopy

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16
Q

Mx of patients who have been treated for CIN 1/2/3

A

Test of cure repeat cervical sample at 6 months

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17
Q

Mx cervical ectropion

A

Ablative treatment such as cold coagulation

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18
Q

Primary dysmenorrhoea =
Mx (3)

A

No underlying pelvic pathology
Pain during and a few hours prior to the period starting
Mx mefanamic acid and ibuprofen
2nd line COCP

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19
Q

Secondary dysmenorrhoea (how does it differ from primary)

CKS Mx

A

Usually starts a few days prior to the period
Refer all patients with secondary dysmenorrhoea to gynae

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20
Q

Ectopic pregnancy bHCG

A

> 1500

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21
Q

Endometrial cancer is classically seen in which group of women?

A

Post menopausal

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22
Q

RF endometrial cancer (9)

A

Nulliparity
Early menarche
Late menopause
Obesity
Unopposed oestrogen
DM
Tamoxifen
PCOS
Hereditary colorectal ca

23
Q

Cervical versus endometrial ca RF

A

Early first intercourse
High parity

Endo - nulliparity, late menopause

Smoking and COCP RF for cervical but protective for endo ca

24
Q

Symptoms of endometrial ca (2)

A

PMB, IMB in premenopausal women

25
Ix for suspected endometrial ca Who gets put on a 2ww? TVUS ET less than ?mm = high negative predictive value Ix (2)
>=55yo with PMB = 2ww TVUS ET <4mm = high negative predictive value Hysteroscopy with endometrial biopsy
26
Mx endo ca
TAH + BSO +/- post op RT OR Progestogen therapy if frail and old
27
Protective factors for endometrial ca
COCP and smoking
28
Endometrial hyperplasia feature (1) Mx Simple (2) Atypia (1)
IMB/ abnormal vaginal bleeding Mx if simple - high dose prog and repeat sampling in 3-4 months or mirena Atypia - hysterectomy
29
Endometriosis mx 1st line 2nd line
1st line NSAIDs/ paracetamol 2nd line COCP or progestogens (medroxyprogesterone acetate)
30
FGM types (4)
1 partial or total removal of clitoris/ prepuce 2 partial or total removal of clitoris and labia minora 3 narrowing of vaginal orifice 4 all other harmful procedures
31
Fibroid degeneration symptoms (4) Mx
Low grade fever, pain, vomiting, pregnancy Mx resolve within 4-7 days rest and analgesia
32
HMB Mx If does not (2) and does require contraception (3)
If doesn't require contraception Mefanamic acid TXA (Start of first day of period) If does 1. Mirena 2. COCP 3. Long acting progestogens
33
What can be used in the short term to rapidly stop HMB?
Norethisterone 5mg TDS
34
What is a blighted ovum?
Gestational sac >25mm but no embryonic or fetal part is seen
35
TOP Gestation Who is needed to sign?
K24 x2 medical practitioners (or one in an emergency)
36
TOP Mx
K15 D&evacuation
37
Semen analysis Abstinence for how long? Sample to be delivered in what time period?
3-5 days 1 hour
38
Normal semen results volume pH Sperm concentration Morphology Motility Vitality
Normal semen results* volume > 1.5 ml pH > 7.2 sperm concentration > 15 million / ml morphology > 4% normal forms motility > 32% progressive motility vitality > 58% live spermatozoa
39
Definition of recurrent miscarriages
3 or more consecutive miscarriages
40
Causes of recurrent miscarriages (7)
Antiphospholipid syndrome PCOS DM Thyroid issues Uterine septum Smoking Parental chromosomal abnormalities
41
Mx pruritus vulvae
Showers not baths Emmolients OD Underlying conditions = topical steroids Seborrhoeic dermatitis - anitfungal combined with steroid
42
Pruritus vulvae usually has ...
An underlying cause
43
HRT complications HINT BEoVIS
Increased risk of Breast ca EndOmetrial ca Ovarian ca VTE Ischaemic heart disease if taken more than 10 years after menopause Stroke
44
Hyperemesis triad definition:
Triad: 5% pre-pregnancy weight loss Dehydration Electrolyte imbalance
45
Hyperemesis Mx 1st line (3) 2nd line (2)
1st line PO cyclizine/ PO promethazine/ PO prochlorperazine 2nd line ondansetron/ metoclopramide
46
Which anti-emetic can increase the risk of cleft lip/palate?
Ondansetron
47
Investigations for infertility (2)
D21 serum prog + semen analysis
48
D21 prog interpretation
<16 = repeat, if consistently low then refer to fertility clinic 16-30 repeat >30 indicates ovulation
49
Counselling for infertility: Medication BMI Sex how often?
1. Folic acid 2. BMI 20-25 3. Regular sexual intercourse every 2-3 days
50
Define premature ovarian insufficiency
Onset of menopausal symptoms before the age of 40
51
Hormone levels in premature ovarian insufficiency FSH LH oestradiol Numbers for FSH and LH
Raised FSH LH FSH >40 Must be demonstrated on 2 blood samples taken 4-6 weeks apart Low oestradiol <100
52
Mx premature ovarian insufficiency
COCP until average age of menopause (51yo) Then HRT
53
Meig's syndrome
Benign ovarian tumour (usually a fibroma) associated with ascites and pleural effusion