Autoantibodies Flashcards Preview

USMLE Step 1 > Autoantibodies > Flashcards

Flashcards in Autoantibodies Deck (23):
1

Anti-ACh receptor

Myasthenia gravis

2

Anti-basement membrane

Goodpasteure syndrome

3

Anticardiolipin, lupus anticoagulant

SLE, antiphospholipid syndrome

4

Anticentromere

Limited scleroderma (CREST syndrome)

5

Anti-desmosome (anti-desmoglein)

Pemphigus vulgaris

6

Anti-dsDNA, anti-Smith

SLE

7

Anti-glutamic acid decarboxylase (GAD-65)

Type 1 diabetes mellitus

8

Antihemidesmosomes

Bullous pemphigoid

9

Anti-histone

Drug-induced lupus

10

Anti-Jo-1 (anti-histidyl-tRNA synthetase), anti-SRP, anti-Mi-2

Polymyositis, dermatomyositis

11

Antimicrosomal, antithyroglobulin

Hashimoto thyroiditis

12

Antimitochondrial

Primary biliary cirrhosis

13

Antinuclear antibodies

SLE, sjogren synd, scleroderma, polymyositis, dermatomyositis, RA, JIA, MCID

14

Antiparietal cell

Pernicious anemia

15

Anti-Scl-70 (anti-DNA topoisomerase I)

Scleroderma (diffuse)

16

Anti-smooth muscle

Autoimmune hepatitis

17

Anti-SSA, anti-SSB (anti-Ro, anti-La)

Sjogren syndrome

18

Anti-TSH receptor

Graces disease

19

Anti-U1 RNP (ribronucleoprotein)

Mixed connective tissue disorder

20

IgA anti-endomysial, IgA anti-tissue transglutaminase

Celiac disease

21

MPO-ANCA/p-ANCA

Microscopic polyangiitis, eosinophilic granulomatosis with polyangitis (Churg-Strauss syndrome)

22

PR3-ANCA/c-ANCA

Granulomatosis with polyangiitis (Wegener)

23

Rheumatoid factor (IgM antibody that targets IgG Fc region), anti-CCP (more specific)

Rheumatoid arthritis