Flashcards in B LYMPHOCYTES AND HUMORAL IMMUNITY Deck (23)
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1
How does the antigen enter the B cell
endocytosis
2
What happens after endocytosis
it gets presented on the surfaced (processed), and T-cells bind to the processes antigens & stimulates the B-cell to divide by mitsos
3
What does the division of B-cells produce
plasma cells
4
What do plasma cells produce
a group of antibodies all complementary to a specific foreign antigen
5
Give an example of a pathogen that also causes toxins
cholera
6
What does each toxin molecule also act as
an antigen
7
What are monoclonal antibodies produced by
the clones of B cells (plasma cells)
8
What are monoclonal antibodies
antibodies that target the same antigens
9
What do the cells produced in the clone of B cells become (2 points)
1) plasma cells
2) memory cells
10
What do plasma cells do
secrete antibodies usually into blood plasma
11
How long do plasma cells survive for
for a few days
12
Are B cells present since and what happens when a pathogen is present
birth, they multiply
13
How many antibodies can each plasma cell make every second
2000
14
What do the antibodies secreted by plasma cells do
destroy the antigen
15
What is the production of antibodies and memory cells known as
primary immune response
16
What is the primary immune response
the production of antibodies and memory cells
17
What are memory cells responsible for
secondary immune response
18
How long do memory cells live for
decades
19
Where are memory cells kept
circulating in the blood and tissue fluid
20
What are memory cells for
future infection
21
What do memory cells provide
long-term immunity
22
Describe the role of B cells in the immune response (7 points) - from antigens detected
1) surface of antigens taken up by B-cells
2) B-cells present the antigens on their surface
3) Helper T-cells attach to the processes antigens on B-cells and activates the B-cells
4) B-cell is activated to divide by mitosis to give a clone of plasma cells
5) cloned plasma cells produce and secrete the specific antibody that fits the antigen on pathogens surface
6) antibody attaches to antigen on pathogen and destroys it
7) some B cells develop into memory cells
23
