B8-071 Treatment of Male Sexual Disorders

Question 1

testosterone deficiency is defined as 2 morning levels less than […] ng + symptoms

Answer 1

300

Question 2

inability to consistently achieve and maintain a satisfactory erection for sexual activity

Answer 2

erectile dysfunction

Question 3

why is it important to identify underlying comorbid conditions in ED patients?

Answer 3

high correlation of underlying CVD/diabetes

Question 4

what is the mechanism of PDE5 inhibitors?

Answer 4

increase cGMP –> NO –> smooth muscle relaxation

Question 5

-afils

Answer 5

PDE5 inhibitors

Question 6

major contraindication to PDE5 inhibitors

Answer 6

nitrates for chest pain

Question 7

men with ED and TD have better benefit when a PDE5i is combined with […]

Answer 7

testosterone therapy

Question 8

ED med that bypasses the nerves

also can be used in patients that fear injections

Answer 8

MUSE (alporatadil)

urethral suppository

Question 9

persistent erection lasting 4 or more hours

Answer 9

priapism

Question 10

which type of priapism is more dangerous?

Answer 10

low flow

Question 11

[high vs low flow priapism]

painful
glans is soft

Answer 11

low flow

Question 12

[high vs low flow priapism]

caused by sickle cell disease

Answer 12

low flow

Question 13

[high vs low flow priapism]

can be caused by trazadone, cocaine, and prazosin

Answer 13

low flow

Question 14

[high vs low flow priapism]

can be caused by incorrect use of intracavernosal agents

Answer 14

low flow

Question 15

treatment for low flow priapism

Answer 15

irrigation & distal shunts

(no proximal shunts)

Question 16

[high vs low flow priapism]
cause tissue death/necrosis

Answer 16

low flow

Question 17

[high vs low flow priapism]

non-painful
glans full

Answer 17

high flow

Question 18

[high vs low flow priapism]

caused by trauma resulting in AV fistula

Answer 18

high flow

Question 19

high vs low blood flow priapism can be determined via what test?

Answer 19

ABG

Question 20

treatment of high flow priapism

Answer 20

embolization

Question 21

when using VED, patients should not wear the ring greater than […] min

Answer 21

30 min

Question 22

bleeding/clotting disorders are a contraindication to what ED treatment?

Answer 22

VED

Question 23

acquired penile deformity due to fibrosis

Answer 23

peyronie’s disease

Question 24

most common cause of delayed ejaculation

Answer 24

SSRIs

(followed by neurologic diseases)

Question 25

common causes of premature ejaculation

Answer 25

anxiety, ED, TD, thyroid

Question 26

common causes of aspermia

Answer 26

DM, autonomic dysfunction, previous surgery

Question 27

"lack of sex drive" refers to

Answer 27

libido

Question 28

the most common disorders affecting libido include disturbances in [3]

Answer 28

testosterone levels pysch disorders hormone disorders

Question 29

physiologically, an erection is the result of increased [...] and decreased [...] to the penis

Answer 29

physiologically, an erection is the result of increased [blood flow] and decreased [outflow] to the penis

Question 30

[...] stimulation results in ejaculation and detumescence

Answer 30

sympathetic

Question 31

MOA of PDE 5i

Answer 31

inhibit cGMP breakdown results in increased NO/decreased calcium -->smooth muscle relaxation --> increased blood flow via vasodilation

Question 32

which PDE 5i has the longest half-life?

Answer 32

tadalafil

Question 33

[...] is the best test to determine high flow priapism vs. low flow

Answer 33

penile blood flow

Question 34

a blood gas with a pO2 below [...] is diagnostic of low flow priapism

Answer 34

40

Question 35

erection is a function of the [...] nervous system

Answer 35

parasympathetic Point, squeeze, shoot

Question 36

erection: NO leads to the increase of [....], allowing for smooth muscle relaxation

Answer 36

cGMP

Question 37

NE leads to the increase of [...], allowing for smooth muscle contraction --> antierectlice

Answer 37

intracellular Ca++

Question 38

emission is a function of the [...] nervous system

Answer 38

sympathetic Point, squeeze, shoot

Question 39

MOA of PDE 5i

Answer 39

decrease breakdown of cGMP